Aron Charles Eklund

  1. 2014
  2. E-pub ahead of print
  3. Published

    The comparison of thrombocytosis and platelet-lymphocyte ratio as potential prognostic markers in colorectal cancer. / Baranyai, Zsolt; Krzystanek, Marcin; Josa, Valeria; Dede, Kristof; Ágoston, E.; Szasz, A. Marcell; Sinko, Daniel; Szarvas, Viktor; Salamon, Ferenc; Eklund, Aron Charles; Szallasi, Zoltan Imre; Jakab, Ferenc.

    In: Thrombosis and Haemostasis, Vol. 111, No. 3, 2014, p. 483-490.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  4. 2013
  5. Published
  6. Published

    Biasogram: visualization of confounding technical bias in gene expression data.. / Krzystanek, Marcin; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: P L o S One, Vol. 8, No. 4, 2013, p. e61872.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  7. Published

    Deconvoluting complex tissues for expression quantitative trait locus-based analyses. / Seo, Ji-Heui; Li, Qiyuan; Fatima, Aquila; Eklund, Aron Charles; Szallasi, Zoltan Imre; Polyak, Kornelia; Richardson, Andrea L.; Freedman, Matthew L.

    In: Royal Society of London. Philosophical Transactions B. Biological Sciences, Vol. 368, No. 1620, 2013, p. 20120363-20120363.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  8. Published

    Methods for predicting anti-cancer response. / Szallasi, Zoltan Imre (Inventor); Eklund, Aron Charles (Inventor); Birkbak, Nicolai Juul (Inventor); Richardson, Andrea L. (Inventor); Silver, Daniel P. (Inventor); Wang, Zhigang (Inventor).

    IPC No.: C12Q1/68. Patent No.: WO2013130347. Sep 06, 2013.

    Publication: ResearchPatent – Annual report year: 2012

  9. Published

    The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.. / Szász, Attila Marcell; Li, Qiyuan; Eklund, Aron Charles; Sztupinszki, Zsófia; Rowan, Andrew; Tőkés, Anna-Mária; Székely, Borbála; Kiss, András; Szendrői, Miklós; Győrffy, Balázs; Szallasi, Zoltan Imre; Swanton, Charles; Kulka, Janina.

    In: PloS one., Vol. 8, No. 2, 2013, p. e56707.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  10. Published

    Tumor Mutation Burden Forecasts Outcome in Ovarian Cancer with BRCA1 or BRCA2 Mutations. / Birkbak, Nicolai Juul; Kochupurakkal, Bose; Gonzalez-Izarzugaza, Jose Maria; Eklund, Aron Charles; Li, Yang; Liu, Joyce; Szallasi, Zoltan Imre; Matulonis, Ursula A. ; Richardson, Andrea L. ; Iglehart, J. Dirk ; Wang, Zhigang C.

    In: P L o S One, Vol. 8, No. 11, e80023, 2013.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  11. 2012
  12. Published

    Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. / Gerlinger, Marco; Rowan, Andrew J.; Horswell, Stuart; Larkin, James; Endesfelder, David; Gronroos, Eva; Martinez, Pierre; Matthews, Nicholas; Stewart, Aengus; Tarpey, Patrick; Varela, Ignacio; Phillimore, Benjamin; Begum, Sharmin; McDonald, Neil Q.; Butler, Adam; Jones, David; Raine, Keiran; Latimer, Calli; Santos, Claudio R.; Nohadani, Mahrokh; Eklund, Aron Charles; Spencer-Dene, Bradley; Clark, Graham; Pickering, Lisa; Stamp, Gordon; Gore, Martin; Szallasi, Zoltan Imre; Downward, Julian; Futreal, P. Andrew; Swanton, Charles.

    In: New England Journal of Medicine, Vol. 366, No. 10, 2012, p. 883-892.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  13. Published
  14. Published

    Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents. / Birkbak, Nicolai J.; Wang, Zhigang C.; Kim, Ji-Young; Eklund, Aron C.; Li, Qiyuan; Tian, Ruiyang; Bowman-Colin, Christian; Li, Yang; Greene-Colozzi, April; Iglehart, J. Dirk; Tung, Nadine; Ryan, Paula D.; Garber, Judy E.; Silver, Daniel P.; Szallasi, Zoltan; Richardson, Andrea L.

    In: Cancer Drug Discovery and Development, Vol. 2, No. 4, 2012, p. 366-375.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  15. 2011
  16. Published

    Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer. / Roylance, Rebecca; Endesfelder, David; Gorman, Patricia; Sander, Jil; Tomlinson, Ian; M. Hanby, Andrew; Speirs, Valerie; L. Richardson, Andrea; Birkbak, Nicolai Juul; Eklund, Aron Charles; Downward, Julian; Kschischo, Maik; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Epidemiology, Biomarkers & Prevention, 22.07.2011, p. 2184-2197.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  17. Published

    Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Desmedt, Christine; Haibe-Kains, Benjamin; Sotiriou, Christos; Symmans, W. Fraser; Pusztai, Lajos; Brunak, Søren; Richardson, Andrea L; Szallasi, Zoltan Imre.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 310.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  18. Published

    Jetset: selecting the optimal microarray probe set to represent a gene. / Li, Qiyuan; Birkbak, Nicolai Juul; Gyorffy, Balazs; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 474.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  19. Published

    Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer. / Birkbak, Nicolai Juul; Eklund, Aron Charles; Li, Qiyuan; McClelland, Sarah E.; Endesfelder, David; Tan, Patrick; Tan, Iain B.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 10, 2011, p. 3447-3452.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  20. Published
  21. 2010
  22. Published

    A focused, PCR based gene expression signature to refine grade in breast cancer. / Szasz, A.; Tokes, A. M.; Szittya, L.; Baranyak, Z. S.; Szekely, B.; Eklund, Aron Charles; Li, Qiyuan; Swanton, C.; Szallasi, Zoltan Imre; Kulka, J.

    In: EJC SUPPLEMENTS, Vol. 8, No. 3, 2010, p. 226-226.

    Publication: ResearchConference abstract in journal – Annual report year: 2010

  23. Published

    An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. / Györffy, B; Lanczky, A; Eklund, Aron Charles; Denkert, Carsten; Budczies, J; Li, Qiyuan; Szallasi, Zoltan Imre.

    In: Breast Cancer Research and Treatment, Vol. 123, No. 3, 2010, p. 725-731.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  24. Published

    Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials. / Juul, Nicolai Stefan; Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Burrell, RA; Gerlinger, M; Valero, V; Andreopoulou, E; Esteva, FJ; Symmans, WF; Desmedt, C; Haibe-Kains, B; Sotiriou, C; Pusztai, L; Swanton, C.

    In: Lancet Oncology, Vol. 11, No. 4, 2010, p. 358-365.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  25. Published

    Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer. / Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Juul, Nicolai Stefan; Silver, Daniel P.; Richardson, Andrea L.; Wang, Zhigang C.; Leong, Chee-Onn; Calogrias, Diana; Buraimoh, Ayodele; Fatima, Aquila; Gelman, Rebecca S.; Ryan, Paula D.; Tung, Nadine M.; De Nicolo, Arcangela; Ganesan, Shridar; Miron, Alexander; Colin, Christian; Sgroi, Dennis C.; Ellisen, Leif W.; Winer, Eric P.; Garber, Judy E.

    In: Journal of Clinical Oncology, Vol. 28, No. 7, 2010, p. 1145-1153.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  26. Published

    Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Haibe-Kains, B.; Workman, Christopher; Richardson, A.L.; Szallasi, Zoltan Imre; Swanton, C.

    In: P L o S One, Vol. 5, No. 12, 2010.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  27. Published
  28. Published

    PGC-1{alpha}, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease. / Zheng, B.; Liao, Z.; Locascio, J.J.; Lesniak, K.A.; Roderick, S.S.; Watt, M.L.; Eklund, Aron Charles; Zhang-James, Y.; Kim, P.D.; Hauser, M.A.; Grünblatt, E.; Moran, L.B.; Mandel, S.A.; Riederer, P.; Miller, R.M.; Federoff, H.J.; Wüllner, U.; Papapetropoulos, S.; Youdim, M.B.; Cantuti-Castelvetri, I.; Young, A.B.; Vance, J.M.; Davis, R.L.; Hedreen, J.C.; Adler, S.H.; Beach, T.G.; Graeber, M.B.; Middleton, F.A.; Rochet, J.C.; Scherzer, C.R.

    In: Science Translational Medicine, Vol. 2, No. 52, 2010, p. 52-73.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  29. Published

    Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets. / Swanton, C.; Larkin, J.M.; Gerlinger, M.; Eklund, Aron Charles; Howell, M.; Stamp, G.; Downward, J.; Gore, M.; Futreal, P.A.; Escudier, B.; Andre, F.; Albiges, L.; Beuselinck, B.; Oudard, S.; Hoffmann, J.; Gyorffy, B.; Torrance, C.; Boehme, K.A.; Volkmer, H.; Toschi, L.; Nicke, B.; Beck, Marlene; Szallasi, Zoltan Imre.

    In: Genome Medicine, Vol. 2, No. 8, 2010.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  30. 2009
  31. Published

    A Functional Metagene Incorporating TTK Protein Kinase, Aurora Kinase B and Glucosylceramide Synthase Predicts Response to Treatment in Primary Breast Cancer. / Juul, Nicolai Stefan; Eklund, Aron Charles; Li, Qiyuan; Downward, J.; Burrell, R.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 602S-602S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

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