Novo Nordisk Foundation Center for Biosustainability

  1. 2015
  2. Published
  3. Published

    CTX-M-1 β-lactamase expression in Escherichia coli is dependent on cefotaxime concentration, growth phase and gene location.. / Kjeldsen, Thea S. B.; Overgaard, Martin; Nielsen, Søren S.; Bortolaia, Valeria; Jelsbak, Lotte; Sommer, Morten Otto Alexander; Guardabassi, Luca; Olsen, John E.

    In: Journal of Antimicrobial Chemotherapy, Vol. 70, No. 1, 2015, p. 62-70.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  4. Published

    Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production bySaccharomyces cerevisiae. / Martínez, José L.; Liu, Lifang; Petranovic, Dina; Nielsen, Jens.

    In: Biotechnology and Bioengineering, Vol. 112, No. 1, 2015, p. 181–188.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  5. Published

    Fast Swinnex Filtration (FSF): A fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media. / McCloskey, Douglas; Utrilla, Jose; Naviaux, Robert K.; Palsson, Bernhard O.; Feist, Adam.

    In: Metabolomics, Vol. 11, No. 1, 2015, p. 198-209.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  6. Published
  7. Published

    Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium. / LaCroix, Ryan A.; Sandberg, Troy E.; O'Brien, Edward J.; Utrilla, Jose; Ebrahim, Ali; Guzman, Gabriela I.; Szubin, Richard; Palsson, Bernhard; Feist, Adam.

    In: Applied and Environmental Microbiology, Vol. 81, No. 1, 2015, p. 2017-30.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. 2014
  9. Published

    3HP TOLERANCE. / Kildegaard, Kanchana Rueksomtawin (Inventor); Borodina, Irina (Inventor); Förster, Jochen (Inventor); Nielsen, Jens (Inventor).

    Patent No.: WO2014198841. Dec 18, 2014.

    Publication: ResearchPatent – Annual report year: 2014

  10. Published
  11. Published

    A compendium of genetic variant data. / Cardoso, Joao; Schöning, Lars Yannik; Herrgard, Markus; Sonnenschein, Nikolaus.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  12. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.. / Lindemose, Søren; Jensen, Michael Krogh; de Velde, Jan Van; O'Shea, Charlotte; Heyndrickx, Ken S.; Workman, Christopher; Vandepoele, Klaas; Skriver, Karen; De Masi, Federico.

    In: Nucleic Acids Research, Vol. 42, No. 12, 2014, p. 7681-7693.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  13. Published

    Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals. / Borodina, Irina; Nielsen, Jens.

    In: Biotechnology Journal, Vol. 9, No. 5, 2014, p. 609-620.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  14. Published

    Ageing of atrazine in manure amended soils assessed by bioavailability to Pseudomonas sp. strain ADP. / Glæsner, Nadia; Bælum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    In: Biodegradation, Vol. 25, No. 2, 2014, p. 217-225.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  15. Published

    A kinetic model of thiamine biosynthesis in Escherichia coli. / Matos, Marta; Herrgard, Markus; Andersen, Mikael Rørdam; Sonnenschein, Nikolaus.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  16. Published

    A model‐driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K‐12 MG1655 that is biochemically and thermodynamically consistent. / McCloskey, Douglas; Gangoiti, Jon A.; King, Zachary A.; Naviaux, Robert K.; Barshop, Bruce A.; Palsson, Bernhard; Feist, Adam.

    In: Biotechnology and Bioengineering, Vol. 111, No. 4, 2014, p. 803-815.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  17. Published

    A new high-throughput LC-MS method for the analysis of complex fructan mixtures.. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Courtin, Christophe M.; Harrison, Scott James.

    In: Analytical and Bioanalytical Chemistry, Vol. 406, No. 19, 2014, p. 4785-4788.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  18. Published

    An integrated catalog of reference genes in the human gut microbiome. / Li, Junhua; Jia, Huijue; Cai, Xianghang; Zhong, Huanzi; Feng, Qiang; Sunagawa, Shinichi; Arumugam, Manimozhiyan; Kultima, Jens Roat; Prifti, Edi; Nielsen, Trine; Juncker, Agnieszka; Nielsen, Henrik Bjørn; Brunak, Søren.

    In: Nature Biotechnology, Vol. 32, No. 8, 2014, p. 834-841.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  19. E-pub ahead of print

    Antibiofilm Properties of Acetic Acid. / Bjarnsholt, Thomas; Alhede, Morten; Jensen, Peter Østrup; Nielsen, Anne K.; Johansen, Helle Krogh; Homøe, Preben; Høiby, Niels; Givskov, Michael Christian; Kirketerp-Møller, Klaus.

    In: Advances in Wound Care, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  20. Published

    Application of a controllable degron strategy for metabolic engineering. / Knuf, Christoph; Maury, Jerome; Jacobsen, Simo Abdessamad; Forster, Jochen.

    In: New Biotechnology, Vol. 31, 2014, p. S163.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  21. E-pub ahead of print

    Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae. / Borodina, Irina; Li, Mingji.

    In: F E M S Yeast Research, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  22. E-pub ahead of print
  23. E-pub ahead of print
  24. Published

    A sustainable route to produce the scytonemin precursor using Escherichia coli. / Malla, Sailesh; Sommer, Morten O. A.

    In: Green Chemistry, Vol. 16, No. 6, 2014, p. 3255-3265.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  25. Published
  26. Published

    Bacterial diversity in snow on North Pole ice floes. / Hauptmann, Aviaja Zenia Edna Lyberth; Stibal, Marek ; Bælum, Jacob; Sicheritz-Pontén, Thomas; Brunak, Søren; Bowman, Jeff S.; Hansen, Lars H. ; Jacobsen, Carsten S.; Blom, Nikolaj.

    In: Extremophiles, Vol. 18, 2014, p. 945-951.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  27. Published

    Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. / Liu, Lifang; Martínez, José L.; Liu, Zihe; Petranovic, Dina; Nielsen, Jens.

    In: Metabolic Engineering, Vol. 21, 2014, p. 9-16.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  28. Published

    Bioelectrochemical reduction of carbon dioxide by pure culture at the cathode. / Aryal, Nabin; Tremblay, Pier-Luc; Chen, Leifeng; Höglund, Daniel; Zhang, Tian.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  29. Published

    Biofuels. Altered sterol composition renders yeast thermotolerant.. / Caspeta, Luis; Chen, Yun; Ghiaci, Payam; Feizi, Amir; Buskov, Steen; Hallström, Björn M.; Petranovic, Dina; Nielsen, Jens.

    In: Science, Vol. 346, No. 6205, 2014, p. 75-78.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  30. Published

    Biopharmaceutical protein production bySaccharomyces cerevisiae: current state and future prospects. / Huang, Mingtao; Bao, Jichen; Nielsen, Jens.

    In: Pharmaceutical Bioprocessing, Vol. 2, No. 2, 2014, p. 167-182.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  31. Published

    BioREFINE-2G project – Engineering of industrial yeast strains for production of dicarboxylic acids from side and waste streams. / Stovicek, Vratislav; Chen, Xiao; Borodina, Irina; Förster, Jochen.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  32. Published

    Biosynthesis of Phenylnannolone A, a Multidrug Resistance Reversal Agent from the Halotolerant Myxobacterium Nannocystis pusilla B150. / Bouhired, Sarah M.; Crüsemann, Max; Almeida, Celso; Weber, Tilmann; Piel, Jörn; Schäberle, Till F.; König, Gabriele M.

    In: ChemBioChem, Vol. 15, No. 5, 2014, p. 757-765.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  33. Published

    Biotechnology for renewable chemicals. / Borodina, Irina; Kildegaard, Kanchana Rueksomtawin; Jensen, Niels Bjerg; Sherstyk, Svetlana; Maury, Jerome; Forster, Jochen; Herrgard, Markus; Nielsen, Jens.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  34. Published

    Characterization of Binding Epitopes of CA125 Monoclonal Antibodies. / Marcos-Silva, Lara; Narimatsu, Yoshiki; Halim, Adnan; Campos, Diana; Zhang, Yang; Tarp, Mads A.; Pereira, Pedro J. B.; Mandel, Ulla; Bennett, Eric P.; Valchrushev, Sergey Y.; Levery, Steven B.; David, Leonor; Clausen, Henrik.

    In: Journal of Proteome Research, Vol. 13, No. 7, 2014, p. 3349-3359.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  35. Published

    Coexistence and Within-Host Evolution of Diversified Lineages of Hypermutable Pseudomonas aeruginosa in Long-term Cystic Fibrosis Infections. / Feliziani, Sofia; Marvig, Rasmus Lykke; Lujan, Adela M.; Moyano, Alejandro J.; Di Rienzo, Julio A.; Johansen, Helle Krogh; Molin, Søren; Smania, Andrea M.

    In: P L o S Genetics, Vol. 10, No. 10, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  36. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds. / Geertz-Hansen, Henrik Marcus; Blom, Nikolaj; Feist, Adam; Brunak, Søren; Petersen, Thomas Nordahl.

    In: Proteins, Vol. 82, No. 9, 2014, p. 1819-1828.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  37. Published

    Combinatorial Strategies for Improving Multiple-Stress Resistance in Industrially Relevant Escherichia coli Strains.. / Lennen, Rebecca; Herrgard, Markus.

    In: Applied and Environmental Microbiology, Vol. 80, No. 19, 2014, p. 6223-6242.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  38. Published

    Comparing Whole-Genome Sequencing with Sanger Sequencing for spa Typing of Methicillin-Resistant Staphylococcus aureus. / Bartels, Mette Damkjaer; Petersen, Andreas; Worning, Peder; Nielsen, Jesper Boye; Larner-Svensson, Hanna; Johansen, Helle Krogh; Andersen, Leif Percival; Jarlov, Jens Otto; Boye, Kit; Larsen, Anders Rhod; Westh, Henrik.

    In: European Journal of Clinical Microbiology & Infectious Diseases, Vol. 52, No. 12, 2014, p. 4305-4308.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  39. Published

    Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17T (=DSM 44213T) producing (S,S)-N,N′-ethylenediaminedisuccinic acid. / Stegmann, Evi; Albersmeier, Andreas; Spohn, Marius; Gert, Helena; Weber, Tilmann; Wohlleben, Wolfgang; Kalinowski, Jörn; Rückert, Christian.

    In: Journal of Biotechnology, Vol. 189, 2014, p. 46-47.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  40. Published
  41. Published

    Deciphering Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli. / Seo, Sang Woo; Kim, Donghyuk; Latif, Haythem; O'Brien, Edward J.; Szubin, Richard; Palsson, Bernhard.

    In: Nature Communications, Vol. 5, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  42. Published

    Design and application of transcription factor based metabolite sensors in Escherichia coli. / Siedler, Solvej; Stahlhut, Steen Gustav; Bringer, Stephanie; Bott, Michael; Maury, Jerome; Sommer, Morten Otto Alexander.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  43. Published

    Determining the Control Circuitry of Redox Metabolism at the Genome-Scale. / Federowicz, Stephen; Kim, Donghyuk; Ebrahim, Ali; Lerman, Joshua; Nagarajan, Harish; Cho, Byung-kwan; Zengler, Karsten; Palsson, Bernhard.

    In: P L o S Genetics, Vol. 10, No. 4, e1004264, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  44. Published

    Development of a yeast cell factory for production of aromatic products. / Rodriguez Prado, Edith Angelica; Kildegaard, Kanchana Rueksomtawin; Li, Mingji; Borodina, Irina; Nielsen, Jens.

    In: New Biotechnology, Vol. 31, No. Supplement, PG-02, 2014, p. S130-S130.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  45. Published

    Development of Graphene-based novel cathode material in MES system. / Chen, Leifeng; Aryal, Nabin; Ammam, Fariza; Tremblay, Pier-Luc; Zhang, Tian.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  46. Published

    Development of Industrial Yeast Platform Strains. / Bergdahl, Basti; Dato, Laura; Förster, Jochen.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  47. E-pub ahead of print

    Direct Mutagenesis of Thousands of Genomic Targets using Microarray-derived Oligonucleotides. / Bonde, Mads; Kosuri, Sriram; Genee, Hans Jasper; Sarup-Lytzen, Kira; Church, George M.; Sommer, Morten; Wang, Harris H.

    In: A C S Synthetic Biology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  48. Published

    Draft Genome Sequence of Photobacterium halotolerans S2753, Producer of Bioactive Secondary Metabolites.. / Machado, Henrique; Månsson, Maria; Gram, Lone.

    In: Genome Announcements, Vol. 2, No. 3, e00535-14, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  49. Published
  50. Published

    Effects of introducing heterologous pathways on microbial metabolism with respect to metabolic optimality. / Kim, Hyun Uk; Kim, Byoungjin; Seung, Do Young; Yup Lee, Sang.

    In: Biotechnology and Bioprocess Engineering, Vol. 19, No. 4, 2014, p. 660-667.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  51. Published

    Engineering amino acid supply pathways in Chinese hamster ovary cells. / Ley, Daniel; Lund, Anne Mathilde; Rank, Julie; Kildegaard, Helene Faustrup; Andersen, Mikael Rørdam.

    2014. Poster session presented at 9th Danish Conference on Biotechnology and Molecular Biology, Denmark.

    Publication: ResearchPoster – Annual report year: 2014

  52. Published

    Engineering synergy in biotechnology. / Nielsen, Jens; Fussenegger, Martin; Keasling, Jay; Yup Lee, Sang; Liao, James C.; Prather, Kristala; Palsson, Bernhard.

    In: Nature Chemical Biology, Vol. 10, No. 5, 2014, p. 319-322.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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