Novo Nordisk Foundation Center for Biosustainability

  1. 2014
  2. Published
  3. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.. / Lindemose, Søren; Jensen, Michael Krogh; de Velde, Jan Van; O'Shea, Charlotte; Heyndrickx, Ken S.; Workman, Christopher; Vandepoele, Klaas; Skriver, Karen; De Masi, Federico.

    In: Nucleic Acids Research, Vol. 42, No. 12, 2014, p. 7681-7693.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  4. Published

    Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals. / Borodina, Irina; Nielsen, Jens.

    In: Biotechnology Journal, Vol. 9, No. 5, 2014, p. 609-620.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  5. Published

    Ageing of atrazine in manure amended soils assessed by bioavailability to Pseudomonas sp. strain ADP. / Glæsner, Nadia; Bælum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    In: Biodegradation, Vol. 25, No. 2, 2014, p. 217-225.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  6. Published

    A model‐driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K‐12 MG1655 that is biochemically and thermodynamically consistent. / McCloskey, Douglas; Gangoiti, Jon A.; King, Zachary A.; Naviaux, Robert K.; Barshop, Bruce A.; Palsson, Bernhard; Feist, Adam.

    In: Biotechnology and Bioengineering, Vol. 111, No. 4, 2014, p. 803-815.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  7. Published

    A new high-throughput LC-MS method for the analysis of complex fructan mixtures.. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Courtin, Christophe M.; Harrison, Scott James.

    In: Analytical and Bioanalytical Chemistry, Vol. 406, No. 19, 2014, p. 4785-4788.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  8. Published

    An integrated catalog of reference genes in the human gut microbiome. / Li, Junhua; Jia, Huijue; Cai, Xianghang; Zhong, Huanzi; Feng, Qiang; Sunagawa, Shinichi; Arumugam, Manimozhiyan; Kultima, Jens Roat; Prifti, Edi; Nielsen, Trine; Juncker, Agnieszka ; Nielsen, Henrik Bjørn; Brunak, Søren.

    In: Nature Biotechnology, Vol. 32, No. 8, 2014, p. 834-841.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  9. E-pub ahead of print

    Antibiofilm Properties of Acetic Acid. / Bjarnsholt, Thomas; Alhede, Morten; Jensen, Peter Østrup; Nielsen, Anne K.; Johansen, Helle Krogh; Homøe, Preben; Høiby, Niels; Givskov, Michael Christian; Kirketerp-Møller, Klaus.

    In: Advances in Wound Care, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  10. Published

    Application of a controllable degron strategy for metabolic engineering. / Knuf, Christoph; Maury, Jerome; Jacobsen, Simo Abdessamad; Forster, Jochen.

    In: New Biotechnology, Vol. 31, 2014, p. S163.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  11. E-pub ahead of print

    Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae. / Borodina, Irina; Li, Mingji.

    In: F E M S Yeast Research, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  12. E-pub ahead of print
  13. E-pub ahead of print
  14. Published

    A sustainable route to produce the scytonemin precursor using Escherichia coli. / Malla, Sailesh; Sommer, Morten O. A.

    In: Green Chemistry, Vol. 16, No. 6, 2014, p. 3255-3265.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  15. Published
  16. E-pub ahead of print

    Bacterial diversity in snow on North Pole ice floes. / Hauptmann, Aviaja Zenia Edna Lyberth; Stibal, Marek ; Bælum, Jacob; Sicheritz-Pontén, Thomas; Brunak, Søren; Bowman, Jeff S.; Hansen, Lars H. ; Jacobsen, Carsten S.; Blom, Nikolaj.

    In: Extremophiles, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  17. Published

    Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. / Liu, Lifang; Martínez, José L.; Liu, Zihe; Petranovic, Dina; Nielsen, Jens.

    In: Metabolic Engineering, Vol. 21, 2014, p. 9-16.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  18. Published

    Biofuels. Altered sterol composition renders yeast thermotolerant.. / Caspeta, Luis; Chen, Yun; Ghiaci, Payam; Feizi, Amir; Buskov, Steen; Hallström, Björn M.; Petranovic, Dina; Nielsen, Jens.

    In: Science, Vol. 346, No. 6205, 2014, p. 75-78.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  19. Published

    Biopharmaceutical protein production bySaccharomyces cerevisiae: current state and future prospects. / Huang, Mingtao; Bao, Jichen; Nielsen, Jens.

    In: Pharmaceutical Bioprocessing, Vol. 2, No. 2, 2014, p. 167-182.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  20. Published

    Biosynthesis of Phenylnannolone A, a Multidrug Resistance Reversal Agent from the Halotolerant Myxobacterium Nannocystis pusilla B150. / Bouhired, Sarah M.; Crüsemann, Max; Almeida, Celso; Weber, Tilmann; Piel, Jörn; Schäberle, Till F.; König, Gabriele M.

    In: ChemBioChem, Vol. 15, No. 5, 2014, p. 757-765.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  21. Published

    Characterization of Binding Epitopes of CA125 Monoclonal Antibodies. / Marcos-Silva, Lara; Narimatsu, Yoshiki; Halim, Adnan; Campos, Diana; Zhang, Yang; Tarp, Mads A.; Pereira, Pedro J. B.; Mandel, Ulla; Bennett, Eric P.; Valchrushev, Sergey Y.; Levery, Steven B.; David, Leonor; Clausen, Henrik.

    In: Journal of Proteome Research, Vol. 13, No. 7, 2014, p. 3349-3359.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  22. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds. / Geertz-Hansen, Henrik Marcus; Blom, Nikolaj; Feist, Adam; Brunak, Søren; Petersen, Thomas Nordahl.

    In: Proteins, Vol. 82, No. 9, 2014, p. 1819-1828.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  23. Published

    Combinatorial Strategies for Improving Multiple-Stress Resistance in Industrially Relevant Escherichia coli Strains.. / Lennen, Rebecca; Herrgard, Markus.

    In: Applied and Environmental Microbiology, Vol. 80, No. 19, 2014, p. 6223-6242.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  24. Published
  25. Published

    Determining the Control Circuitry of Redox Metabolism at the Genome-Scale. / Federowicz, Stephen; Kim, Donghyuk; Ebrahim, Ali; Lerman, Joshua; Nagarajan, Harish; Cho, Byung-kwan; Zengler, Karsten; Palsson, Bernhard.

    In: P L o S Genetics, Vol. 10, No. 4, e1004264, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  26. Published

    Development of a yeast cell factory for production of aromatic products. / Rodriguez Prado, Edith Angelica; Kildegaard, Kanchana Rueksomtawin; Li, Mingji; Borodina, Irina; Nielsen, Jens.

    In: New Biotechnology, Vol. 31, No. Supplement, PG-02, 2014, p. S130-S130.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  27. E-pub ahead of print

    Direct Mutagenesis of Thousands of Genomic Targets using Microarray-derived Oligonucleotides. / Bonde, Mads; Kosuri, Sriram; Genee, Hans Jasper; Sarup-Lytzen, Kira; Church, George M.; Sommer, Morten; Wang, Harris H.

    In: A C S Synthetic Biology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  28. Published

    Draft Genome Sequence of Photobacterium halotolerans S2753, Producer of Bioactive Secondary Metabolites.. / Machado, Henrique; Månsson, Maria; Gram, Lone.

    In: Genome Announcements, Vol. 2, No. 3, e00535-14, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  29. Published
  30. Published

    Effects of introducing heterologous pathways on microbial metabolism with respect to metabolic optimality. / Kim, Hyun Uk; Kim, Byoungjin; Seung, Do Young; Yup Lee, Sang.

    In: Biotechnology and Bioprocess Engineering, Vol. 19, No. 4, 2014, p. 660-667.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  31. Published

    Engineering amino acid supply pathways in Chinese hamster ovary cells. / Ley, Daniel; Lund, Anne Mathilde; Rank, Julie; Kildegaard, Helene Faustrup; Andersen, Mikael Rørdam.

    2014. Poster session presented at 9. Danish Conference on Biotechnology and Molecular Biology, Denmark.

    Publication: ResearchPoster – Annual report year: 2014

  32. Published

    Engineering synergy in biotechnology. / Nielsen, Jens; Fussenegger, Martin; Keasling, Jay; Yup Lee, Sang; Liao, James C.; Prather, Kristala; Palsson, Bernhard.

    In: Nature Chemical Biology, Vol. 10, No. 5, 2014, p. 319-322.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  33. E-pub ahead of print

    Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production bySaccharomyces cerevisiae. / Martínez, José L.; Liu, Lifang; Petranovic, Dina; Nielsen, Jens.

    In: Biotechnology and Bioengineering, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  34. Published

    Evolution of Escherichia coli to 42 °C and Subsequent Genetic Engineering Reveals Adaptive Mechanisms and Novel Mutations.. / Sandberg, Troy E.; Pedersen, Margit; LaCroix, Ryan A.; Ebrahim, Ali; Bonde, Mads; Herrgard, Markus; Palsson, Bernhard; Sommer, Morten; Feist, Adam.

    In: Molecular Biology and Evolution, Vol. 31, No. 10, 2014, p. 2647-2662.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  35. Published
  36. E-pub ahead of print

    Fast Swinnex Filtration (FSF): A fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media. / McCloskey, Douglas; Utrilla, Jose; Naviaux, Robert K.; Palsson, Bernhard O.; Feist, Adam.

    In: Metabolomics, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  37. E-pub ahead of print

    ‘Forcing the issue’ – Aromatic tuning facilitates stimulus-independent modulation of a two-component signaling circuit. / Nørholm, Morten; von Heijne, Gunnar; Draheim, Roger R.

    In: A C S Synthetic Biology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  38. Published

    Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm, GEM-Path. / Campodonico, Miguel A.; Andrews, Barbara A.; Asenjo, Juan A.; Palsson, Bernhard; Feist, Adam.

    In: Metabolic Engineering, Vol. 25, 2014, p. 140-158.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  39. Published

    Genetically engineered yeast. / Borodina, Irina (Inventor); Kildegaard, Kanchana Rueksomtawin (Inventor); Förster, Jochen (Inventor); Öberg, Fredrik (Inventor).

    IPC No.: C12N15/52. Patent No.: WO2014057036. Apr 17, 2014.

    Publication: ResearchPatent – Annual report year: 2014

  40. Published

    Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae. / Liu, Lifang; Feizi, Amir; Osterlund, Tobias; Hjort, Carsten; Nielsen, Jens.

    In: B M C Systems Biology, Vol. 8, No. 73, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  41. Published

    Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states. / Cho, Byung-Kwan; Kim, Donghyuk; Knight, Eric M.; Zengler, Karsten; Palsson, Bernhard.

    In: Journal of Biology (Online), Vol. 12, No. 4, 4, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  42. Published

    High-throughput screening for industrial enzyme production hosts by droplet microfluidics. / Sjostrom, Staffan L.; Bai, Yunpeng; Huang, Mingtao; Liu, Zihe; Nielsen, Jens; Jönsson, Håkan; Svahn, Helene Andersson.

    In: Lab On a Chip, Vol. 14, No. 4, 2014, p. 806-813.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  43. Published

    How to Fight Back Against Antibiotic Resistance. / Dantas, Gautam; Sommer, Morten.

    In: American Scientist, Vol. 102, No. 1, 2014, p. 42-51.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  44. Published

    Human Intestinal Cells Modulate Conjugational Transfer of Multidrug Resistance Plasmids between Clinical Escherichia coli Isolates.. / Machado, Ana Manuel; Sommer, Morten.

    In: P L o S One, Vol. 9, No. 6, 2014, p. e100739.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  45. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes. / Nielsen, Henrik Bjørn; Almeida, Mathieu; Juncker, Agnieszka; Rasmussen, Simon; Li, Junhua; Sunagawa, Shinichi; Plichta, Damian Rafal; Gautier, Laurent; Pedersen, Anders Gorm; Emmanuelle, Le Chatelier; Pelletier, Eric; Bonde, Ida; Nielsen, Trine; Manichanh, Chaysavanh; Arumugam, Manimozhiyan; Batto, Jean-Michel; dos Santos, Marcelo Bertalan Quintanilha; Blom, Nikolaj; Borruel, Natalia; Burgdorf, Kristoffer S.; Boumezbeur, Fouad; Casellas, Francesc; Doré, Joël; Dworzynski, Piotr; Guarner, Francisco; Hansen, Torben; Hildebrand, Falk; Kaas, Rolf Sommer; Kennedy, Sean; Kristiansen, Karsten; Kultima, Jens Roat; Léonard, Pierre; Levenez, Florence; Lund, Ole; Moumen, Bouziane; Denis, Le Paslier; Pons, Nicolas; Pedersen, Oluf; Prifti, Edi; Qin, Junjie; Raes, Jeroen; Sørensen, Søren; Tap, Julien; Tims, Sebastian; Ussery, David; Yamada, Takuji; Renault, Pierre; Sicheritz-Pontén, Thomas; Bork, Peer; Wang, Jun; Brunak, Søren; Ehrlich, S. Dusko.

    In: Nature Biotechnology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  46. Published

    Identification of Bacterial Small RNAs by RNA Sequencing. / Gómez Lozano, María; Marvig, Rasmus Lykke; Molin, Søren; Long, Katherine.

    Pseudomonas Methods and Protocols. ed. / Alain Filloux; Juan-Luis Ramos. Springer Science+Business Media B.V., 2014. p. 433-456 (Methods in Molecular Biology, Vol. 1149).

    Publication: Research - peer-reviewBook chapter – Annual report year: 2014

  47. Published

    Identification of genes specifically required for the anaerobic metabolism of benzene in Geobacter metallireducens. / Zhang, Tian; Tremblay, Pier-Luc; Chaurasia, Akhilesh Kumar; Smith, Jessica A.; Bain, Timothy S.

    In: Frontiers in Microbiology, Vol. 5, 245, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  48. Published

    Impact of protein uptake and degradation on recombinant protein secretion in yeast. / Tyo, Keith E. J.; Liu, Zihe; Magnusson, Ylva; Petranovic, Dina; Nielsen, Jens.

    In: Applied Microbiology and Biotechnology, Vol. 98, No. 16, 2014, p. 7149-7159.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  49. Published

    Improved Production of a Heterologous Amylase in Saccharomyces cerevisiae by Inverse Metabolic Engineering. / Liu, Zihe; Liu, Lifang; Osterlund, Tobias; Hou, Jin; Huang, Mingtao; Fagerberg, Linn; Petranovic, Dina; Uhlén, Mathias; Nielsen, Jens.

    In: APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 80, No. 17, 2014, p. 5542-5550.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  50. Published

    Improving biotech education through gamified laboratory simulations. / Bonde, Mads; Makransky, Guido; Wandall, Jakob; Larsen, Mette Voldby; Morsing, Mikkel; Jarmer, Hanne Østergaard; Sommer, Morten.

    In: Nature Biotechnology, Vol. 32, No. 7, 2014, p. 694-697.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  51. Published

    In silico tools for the analysis of antibiotic biosynthetic pathways.. / Weber, Tilmann.

    In: International Journal of Medical Microbiology, Vol. 304, 2014, p. 230-235.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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