Novo Nordisk Foundation Center for Biosustainability

  1. 2015
  2. In press

    A logical data representation framework for electricity-driven bioproduction processes. / Patil, Sunil A.; Gildemyn, Sylvia; Pant, Deepak; Zengler, Karsten; Logan, Bruce E.; Rabaey, Korneel.

    In: Biotechnology Advances, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  3. Published
  4. Published

    Applications of computational modeling in metabolic engineering of yeast. / Kerkhoven, Eduard J.; Lahtvee, Petri-Jaan; Nielsen, Jens.

    In: F E M S Yeast Research, Vol. 15, No. 1, 2015, p. 1-13.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  5. Published
  6. Published

    A systems approach to traditional oriental medicine. / Kim, Hyun Uk; Ryu, Jae Yong; Lee, Jong Ok; Lee, Sang Yup.

    In: Nature Biotechnology, Vol. 33, No. 3, 2015, p. 264-268.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  7. Published

    Biorefineries for the production of top building block chemicals and their derivatives. / Choi, Sol; Song, Chan Woo; Shin, Jae Ho; Lee, Sang Yup.

    In: Metabolic Engineering, Vol. 28, 2015, p. 223-239.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. Published

    Bistability in a Metabolic Network Underpins the De Novo Evolution of Colony Switching in Pseudomonas fluorescens. / Gallie, Jenna; Libby, Eric; Bertels, Frederic; Remigi, Philippe; Jendresen, Christian Bille; Ferguson, Gayle C.; Desprat, Nicolas; Buffing, Marieke F.; Sauer, Uwe; Beaumont, Hubertus J. E.; Martinussen, Jan; Kilstrup, Mogens; Rainey, Paul B.

    In: P L o S Biology, Vol. 13, No. 3, e1002109, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  9. E-pub ahead of print
  10. E-pub ahead of print

    Co-evolution of strain design methods based on flux balance and elementary mode analysis. / Machado, Daniel; Herrgard, Markus.

    In: Metabolic Engineering Communications, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  11. Published
  12. Published

    Controllability analysis of transcriptional regulatory networks reveals circular control patterns among transcription factors. / Österlund, Tobias; Bordel, Sergio; Nielsen, Jens.

    In: Integrative Biology, Vol. 7, No. 5, 2015, p. 560-568.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  13. Published
  14. Published

    CTX-M-1 β-lactamase expression in Escherichia coli is dependent on cefotaxime concentration, growth phase and gene location.. / Kjeldsen, Thea S. B.; Overgaard, Martin; Nielsen, Søren S.; Bortolaia, Valeria; Jelsbak, Lotte; Sommer, Morten Otto Alexander; Guardabassi, Luca; Olsen, John E.

    In: Journal of Antimicrobial Chemotherapy, Vol. 70, No. 1, 2015, p. 62-70.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  15. Published

    Design of homo-organic acid producing strains using multi-objective optimization. / Kim, Tae Yong; Park, Jong Myoung; Kim, Hyun Uk; Cho, Kwang Myung; Lee, Sang Yup.

    In: Metabolic Engineering, Vol. 28, 2015, p. 63-73.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  16. E-pub ahead of print

    Development of a VHH-Based Erythropoietin Quantification Assay. / Kol, Stefan; Beuchert Kallehauge, Thomas; Adema, Simon; Hermans, Pim.

    In: Molecular Biotechnology, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  17. Published
  18. Published

    Diversity of small RNAs expressed in Pseudomonas species. / Gomez-Lozano, Mara; Marvig, Rasmus Lykke; Molina-Santiago, Carlos; Tribelli, Paula Maria; Ramos, Juan-Luis; Molin, Søren.

    In: Environmental Microbiology Reports, Vol. 7, No. 2, 2015, p. 227-236.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  19. Published

    Electrifying microbes for the production of chemicals. / Tremblay, Pier-Luc; Zhang, Tian.

    In: Frontiers in Microbiology, Vol. 6, 201, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  20. Published

    Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production by Saccharomyces cerevisiae. / Martínez, José L.; Liu, Lifang; Petranovic, Dina; Nielsen, Jens.

    In: Biotechnology and Bioengineering, Vol. 112, No. 1, 2015, p. 181–188.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  21. Published

    Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK. / Nicastro, Raffaele; Tripodi, Farida; Guzzi, Cinzia; Reghellin, Veronica; Khoomrung, Sakda; Capusoni, Claudia; Compagno, Concetta; Airoldi, Cristina; Nielsen, Jens; Alberghina, Lilia; Coccetti, Paola.

    In: B B A - Molecular Cell Research, Vol. 1853, No. 7, 2015, p. 1615-1625.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  22. Published

    Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients. / Marvig, Rasmus Lykke; Madsen Sommer, Lea Mette; Jelsbak, Lars; Molin, Søren; Johansen, Helle Krogh.

    In: Future Microbiology, Vol. 10, No. 4, 2015, p. 599-611.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  23. Published

    Extended spectrum beta-lactamase-producing Escherichia coli forms filaments as an initial response to cefotaxime treatment. / Kjeldsen, Thea S. B.; Sommer, Morten Otto Alexander; Olsen, John E.

    In: B M C Microbiology, Vol. 15, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  24. Published

    Fast and sensitive detection of indels induced by precise gene targeting. / Yang, Zhang; Steentoft, Catharina; Hauge, Camilla; Hansen, Lars; Thomsen, Allan Lind; Niola, Francesco; Vester-Christensen, Malene Bech; Frödin, Morten; Clausen, Henrik; Wandall, Hans H.; Bennett, Eric P.

    In: Nucleic Acids Research, Vol. 43, No. 9, 20e59-e59, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  25. Published

    Fast Swinnex Filtration (FSF): A fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media. / McCloskey, Douglas; Utrilla, Jose; Naviaux, Robert K.; Palsson, Bernhard O.; Feist, Adam.

    In: Metabolomics, Vol. 11, No. 1, 2015, p. 198-209.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  26. Published

    Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria. / Machado, Henrique; Sonnenschein, Eva; Melchiorsen, Jette; Gram, Lone.

    In: B M C Genomics, Vol. 16, 158, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  27. Published

    How to set up collaborations between academia and industrial biotech companies. / Pronk, Jack T.; Lee, Sang Yup; Lievense, Jeff; Pierce, John; Palsson, Bernhard; Uhlén, Mathias; Nielsen, Jens.

    In: Nature Biotechnology, Vol. 33, No. 3, 2015, p. 237-240.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  28. In press

    Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals. / Jullesson, David; David, Florian; Pfleger, Brian; Nielsen, Jens.

    In: Biotechnology Advances, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  29. Published

    LC-MS analysis reveals the presence of graminan- and neo-type fructans in wheat grains. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Delcour, Jan A.; Van den Ende, Wim; Harrison, Scott James; Courtin, Christophe M.

    In: Journal of Cereal Science, Vol. 61, 2015, p. 133-138.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  30. Published
  31. Published

    Model-driven discovery of underground metabolic functions in Escherichia coli. / Guzmán, Gabriela I.; Utrilla, José; Nurk, Sergey; Brunk, Elizabeth; Monk, Jonathan M.; Ebrahim, Ali; Palsson, Bernhard O.; Feist, Adam M.

    In: Proceedings of the National Academy of Sciences, Vol. 112, No. 3, 2015, p. 929-934.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  32. Published
  33. Published

    New paradigms for metabolic modeling of human cells. / Mardinoglu, Adil; Nielsen, Jens.

    In: Current Opinion in Biotechnology, Vol. 34, 2015, p. 91-97.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  34. Published

    Next-generation genome-scale models for metabolic engineering. / King, Zachary A.; Lloyd, Colton J.; Feist, Adam M.; Palsson, Bernhard O.

    In: Current Opinion in Biotechnology, Vol. 35, 2015, p. 23-29.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  35. Published

    Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia. / Alanin, Mikkel Christian; Johansen, Helle Krogh; Aanaes, Kasper; Høiby, Niels; Pressler, Tanja; Skov, Marianne; Nielsen, Kim Gjerum; Von Buchwald, Christian.

    In: Acta Oto-Laryngologica, Vol. 135, No. 1, 2015, p. 58-63.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  36. Published
  37. Published

    Solid-phase cloning for high-throughput assembly of single and multiple DNA parts. / Lundqvist, Magnus; Edfors, Fredrik; Sivertsson, Åsa; Hallström, Björn M.; Hudson, Elton P.; Tegel, Hanna; Holmberg, Anders; Uhlén, Mathias; Rockberg, Johan.

    In: Nucleic Acids Research, Vol. 43, No. 7, 20e49-e49, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  38. Published

    The architecture of ArgR-DNA complexes at the genome-scale in Escherichia coli. / Cho, Suhyung; Cho, Yoo-Bok; Kang, Taek Jin; Kim, Sun Chang; Palsson, Bernhard; Cho, Byung-Kwan.

    In: Nucleic Acids Research, Vol. 43, No. 6, 2015, p. 3079-3088.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  39. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P-aeruginosa infection - A pilot study. / Skov, Marianne; Pressler, Tacjana; Lykkesfeldt, Jens; Poulsen, Henrik Enghusen; Jensen, Peter Ostrup; Johansen, Helle Krogh; Qvist, Tavs; Kraemer, Dorthe; Hoiby, Niels; Ciofu, Oana.

    In: Journal of Cystic Fibrosis, Vol. 14, No. 2, 2015, p. 211-218.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  40. Published

    The fur Gene as a New Phylogenetic Marker for Vibrionaceae Species Identification. / Machado, Henrique; Gram, Lone.

    In: Applied and Environmental Microbiology, Vol. 81, No. 8, 2015, p. 2745-2752.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  41. Published

    Tissue-based map of the human proteome.. / Uhlén, Mathias; Fagerberg, Linn; Hallström, Björn M.; Lindskog, Cecilia; Oksvold, Per; Mardinoglu, Adil; Sivertsson, Åsa; Kampf, Caroline; Sjöstedt, Evelina; Asplund, Anna; Olsson, IngMarie; Edlund, Karolina; Lundberg, Emma; Navani, Sanjay; Szigyarto, Cristina Al-Khalili; Odeberg, Jacob; Djureinovic, Dijana; Takanen, Jenny Ottosson; Hober, Sophia; Alm, Tove; Edqvist, Per-Henrik; Berling, Holger; Tegel, Hanna; Mulder, Jan; Rockberg, Johan; Nilsson, Peter; Schwenk, Jochen M.; Hamsten, Marica; von Feilitzen, Kalle; Forsberg, Mattias; Persson, Lukas; Johansson, Fredric; Zwahlen, Martin; von Heijne, Gunnar; Nielsen, Jens; Pontén, Fredrik.

    In: Science (New York, N.Y.), Vol. 347, No. 6220, 1260419, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  42. Published

    Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium. / LaCroix, Ryan A.; Sandberg, Troy E.; O'Brien, Edward J.; Utrilla, Jose; Ebrahim, Ali; Guzman, Gabriela I.; Szubin, Richard; Palsson, Bernhard; Feist, Adam.

    In: Applied and Environmental Microbiology, Vol. 81, No. 1, 2015, p. 2017-30.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  43. 2014
  44. Published

    3HP TOLERANCE. / Kildegaard, Kanchana Rueksomtawin (Inventor); Borodina, Irina (Inventor); Förster, Jochen (Inventor); Nielsen, Jens (Inventor).

    Patent No.: WO2014198841. Dec 18, 2014.

    Publication: ResearchPatent – Annual report year: 2014

  45. Published
  46. Published

    A compendium of genetic variant data. / Cardoso, Joao; Schöning, Lars Yannik; Herrgard, Markus; Sonnenschein, Nikolaus.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  47. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.. / Lindemose, Søren; Jensen, Michael Krogh; de Velde, Jan Van; O'Shea, Charlotte; Heyndrickx, Ken S.; Workman, Christopher; Vandepoele, Klaas; Skriver, Karen; De Masi, Federico.

    In: Nucleic Acids Research, Vol. 42, No. 12, 2014, p. 7681-7693.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  48. Published

    Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals. / Borodina, Irina; Nielsen, Jens.

    In: Biotechnology Journal, Vol. 9, No. 5, 2014, p. 609-620.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  49. Published

    Ageing of atrazine in manure amended soils assessed by bioavailability to Pseudomonas sp. strain ADP. / Glæsner, Nadia; Bælum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    In: Biodegradation, Vol. 25, No. 2, 2014, p. 217-225.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  50. Published

    A kinetic model of thiamine biosynthesis in Escherichia coli. / Matos, Marta; Herrgard, Markus; Andersen, Mikael Rørdam; Sonnenschein, Nikolaus.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  51. Published

    A model‐driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K‐12 MG1655 that is biochemically and thermodynamically consistent. / McCloskey, Douglas; Gangoiti, Jon A.; King, Zachary A.; Naviaux, Robert K.; Barshop, Bruce A.; Palsson, Bernhard; Feist, Adam.

    In: Biotechnology and Bioengineering, Vol. 111, No. 4, 2014, p. 803-815.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  52. Published

    A new high-throughput LC-MS method for the analysis of complex fructan mixtures.. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Courtin, Christophe M.; Harrison, Scott James.

    In: Analytical and Bioanalytical Chemistry, Vol. 406, No. 19, 2014, p. 4785-4788.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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