Novo Nordisk Foundation Center for Biosustainability

  1. 2015
  2. Published

    Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium. / LaCroix, Ryan A.; Sandberg, Troy E.; O'Brien, Edward J.; Utrilla, Jose; Ebrahim, Ali; Guzman, Gabriela I.; Szubin, Richard; Palsson, Bernhard; Feist, Adam.

    In: Applied and Environmental Microbiology, Vol. 81, No. 1, 2015, p. 2017-30.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  3. 2014
  4. Published
  5. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.. / Lindemose, Søren; Jensen, Michael Krogh; de Velde, Jan Van; O'Shea, Charlotte; Heyndrickx, Ken S.; Workman, Christopher; Vandepoele, Klaas; Skriver, Karen; De Masi, Federico.

    In: Nucleic Acids Research, Vol. 42, No. 12, 2014, p. 7681-7693.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  6. Published

    Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals. / Borodina, Irina; Nielsen, Jens.

    In: Biotechnology Journal, Vol. 9, No. 5, 2014, p. 609-620.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  7. Published

    Ageing of atrazine in manure amended soils assessed by bioavailability to Pseudomonas sp. strain ADP. / Glæsner, Nadia; Bælum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    In: Biodegradation, Vol. 25, No. 2, 2014, p. 217-225.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  8. Published

    A model‐driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K‐12 MG1655 that is biochemically and thermodynamically consistent. / McCloskey, Douglas; Gangoiti, Jon A.; King, Zachary A.; Naviaux, Robert K.; Barshop, Bruce A.; Palsson, Bernhard; Feist, Adam.

    In: Biotechnology and Bioengineering, Vol. 111, No. 4, 2014, p. 803-815.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  9. Published

    A new high-throughput LC-MS method for the analysis of complex fructan mixtures.. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Courtin, Christophe M.; Harrison, Scott James.

    In: Analytical and Bioanalytical Chemistry, Vol. 406, No. 19, 2014, p. 4785-4788.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  10. Published

    An integrated catalog of reference genes in the human gut microbiome. / Li, Junhua; Jia, Huijue; Cai, Xianghang; Zhong, Huanzi; Feng, Qiang; Sunagawa, Shinichi; Arumugam, Manimozhiyan; Kultima, Jens Roat; Prifti, Edi; Nielsen, Trine; Juncker, Agnieszka; Nielsen, Henrik Bjørn; Brunak, Søren.

    In: Nature Biotechnology, Vol. 32, No. 8, 2014, p. 834-841.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  11. E-pub ahead of print

    Antibiofilm Properties of Acetic Acid. / Bjarnsholt, Thomas; Alhede, Morten; Jensen, Peter Østrup; Nielsen, Anne K.; Johansen, Helle Krogh; Homøe, Preben; Høiby, Niels; Givskov, Michael Christian; Kirketerp-Møller, Klaus.

    In: Advances in Wound Care, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  12. Published

    Application of a controllable degron strategy for metabolic engineering. / Knuf, Christoph; Maury, Jerome; Jacobsen, Simo Abdessamad; Forster, Jochen.

    In: New Biotechnology, Vol. 31, 2014, p. S163.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  13. E-pub ahead of print

    Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae. / Borodina, Irina; Li, Mingji.

    In: F E M S Yeast Research, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  14. E-pub ahead of print
  15. E-pub ahead of print
  16. Published

    A sustainable route to produce the scytonemin precursor using Escherichia coli. / Malla, Sailesh; Sommer, Morten O. A.

    In: Green Chemistry, Vol. 16, No. 6, 2014, p. 3255-3265.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  17. Published
  18. Published

    Bacterial diversity in snow on North Pole ice floes. / Hauptmann, Aviaja Zenia Edna Lyberth; Stibal, Marek ; Bælum, Jacob; Sicheritz-Pontén, Thomas; Brunak, Søren; Bowman, Jeff S.; Hansen, Lars H. ; Jacobsen, Carsten S.; Blom, Nikolaj.

    In: Extremophiles, Vol. 18, 2014, p. 945-951.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  19. Published

    Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. / Liu, Lifang; Martínez, José L.; Liu, Zihe; Petranovic, Dina; Nielsen, Jens.

    In: Metabolic Engineering, Vol. 21, 2014, p. 9-16.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  20. Published

    Biofuels. Altered sterol composition renders yeast thermotolerant.. / Caspeta, Luis; Chen, Yun; Ghiaci, Payam; Feizi, Amir; Buskov, Steen; Hallström, Björn M.; Petranovic, Dina; Nielsen, Jens.

    In: Science, Vol. 346, No. 6205, 2014, p. 75-78.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  21. Published

    Biopharmaceutical protein production bySaccharomyces cerevisiae: current state and future prospects. / Huang, Mingtao; Bao, Jichen; Nielsen, Jens.

    In: Pharmaceutical Bioprocessing, Vol. 2, No. 2, 2014, p. 167-182.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  22. Published

    Biosynthesis of Phenylnannolone A, a Multidrug Resistance Reversal Agent from the Halotolerant Myxobacterium Nannocystis pusilla B150. / Bouhired, Sarah M.; Crüsemann, Max; Almeida, Celso; Weber, Tilmann; Piel, Jörn; Schäberle, Till F.; König, Gabriele M.

    In: ChemBioChem, Vol. 15, No. 5, 2014, p. 757-765.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  23. Published

    Characterization of Binding Epitopes of CA125 Monoclonal Antibodies. / Marcos-Silva, Lara; Narimatsu, Yoshiki; Halim, Adnan; Campos, Diana; Zhang, Yang; Tarp, Mads A.; Pereira, Pedro J. B.; Mandel, Ulla; Bennett, Eric P.; Valchrushev, Sergey Y.; Levery, Steven B.; David, Leonor; Clausen, Henrik.

    In: Journal of Proteome Research, Vol. 13, No. 7, 2014, p. 3349-3359.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  24. Published

    Coexistence and Within-Host Evolution of Diversified Lineages of Hypermutable Pseudomonas aeruginosa in Long-term Cystic Fibrosis Infections. / Feliziani, Sofia; Marvig, Rasmus Lykke; Lujan, Adela M.; Moyano, Alejandro J.; Di Rienzo, Julio A.; Johansen, Helle Krogh; Molin, Søren; Smania, Andrea M.

    In: P L o S Genetics, Vol. 10, No. 10, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  25. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds. / Geertz-Hansen, Henrik Marcus; Blom, Nikolaj; Feist, Adam; Brunak, Søren; Petersen, Thomas Nordahl.

    In: Proteins, Vol. 82, No. 9, 2014, p. 1819-1828.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  26. Published

    Combinatorial Strategies for Improving Multiple-Stress Resistance in Industrially Relevant Escherichia coli Strains.. / Lennen, Rebecca; Herrgard, Markus.

    In: Applied and Environmental Microbiology, Vol. 80, No. 19, 2014, p. 6223-6242.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  27. Published

    Comparing Whole-Genome Sequencing with Sanger Sequencing for spa Typing of Methicillin-Resistant Staphylococcus aureus. / Bartels, Mette Damkjaer; Petersen, Andreas; Worning, Peder; Nielsen, Jesper Boye; Larner-Svensson, Hanna; Johansen, Helle Krogh; Andersen, Leif Percival; Jarlov, Jens Otto; Boye, Kit; Larsen, Anders Rhod; Westh, Henrik.

    In: European Journal of Clinical Microbiology & Infectious Diseases, Vol. 52, No. 12, 2014, p. 4305-4308.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  28. Published

    Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17T (=DSM 44213T) producing (S,S)-N,N′-ethylenediaminedisuccinic acid. / Stegmann, Evi; Albersmeier, Andreas; Spohn, Marius; Gert, Helena; Weber, Tilmann; Wohlleben, Wolfgang; Kalinowski, Jörn; Rückert, Christian.

    In: Journal of Biotechnology, Vol. 189, 2014, p. 46-47.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  29. E-pub ahead of print
  30. Published
  31. Published

    Deciphering Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli. / Seo, Sang Woo; Kim, Donghyuk; Latif, Haythem; O'Brien, Edward J.; Szubin, Richard; Palsson, Bernhard.

    In: Nature Communications, Vol. 5, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  32. Published

    Determining the Control Circuitry of Redox Metabolism at the Genome-Scale. / Federowicz, Stephen; Kim, Donghyuk; Ebrahim, Ali; Lerman, Joshua; Nagarajan, Harish; Cho, Byung-kwan; Zengler, Karsten; Palsson, Bernhard.

    In: P L o S Genetics, Vol. 10, No. 4, e1004264, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  33. Published

    Development of a yeast cell factory for production of aromatic products. / Rodriguez Prado, Edith Angelica; Kildegaard, Kanchana Rueksomtawin; Li, Mingji; Borodina, Irina; Nielsen, Jens.

    In: New Biotechnology, Vol. 31, No. Supplement, PG-02, 2014, p. S130-S130.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  34. E-pub ahead of print

    Direct Mutagenesis of Thousands of Genomic Targets using Microarray-derived Oligonucleotides. / Bonde, Mads; Kosuri, Sriram; Genee, Hans Jasper; Sarup-Lytzen, Kira; Church, George M.; Sommer, Morten; Wang, Harris H.

    In: A C S Synthetic Biology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  35. Published

    Draft Genome Sequence of Photobacterium halotolerans S2753, Producer of Bioactive Secondary Metabolites.. / Machado, Henrique; Månsson, Maria; Gram, Lone.

    In: Genome Announcements, Vol. 2, No. 3, e00535-14, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  36. Published
  37. Published

    Effects of introducing heterologous pathways on microbial metabolism with respect to metabolic optimality. / Kim, Hyun Uk; Kim, Byoungjin; Seung, Do Young; Yup Lee, Sang.

    In: Biotechnology and Bioprocess Engineering, Vol. 19, No. 4, 2014, p. 660-667.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  38. Published

    Engineering amino acid supply pathways in Chinese hamster ovary cells. / Ley, Daniel; Lund, Anne Mathilde; Rank, Julie; Kildegaard, Helene Faustrup; Andersen, Mikael Rørdam.

    2014. Poster session presented at 9. Danish Conference on Biotechnology and Molecular Biology, Denmark.

    Publication: ResearchPoster – Annual report year: 2014

  39. Published

    Engineering synergy in biotechnology. / Nielsen, Jens; Fussenegger, Martin; Keasling, Jay; Yup Lee, Sang; Liao, James C.; Prather, Kristala; Palsson, Bernhard.

    In: Nature Chemical Biology, Vol. 10, No. 5, 2014, p. 319-322.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  40. E-pub ahead of print

    Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production bySaccharomyces cerevisiae. / Martínez, José L.; Liu, Lifang; Petranovic, Dina; Nielsen, Jens.

    In: Biotechnology and Bioengineering, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  41. Published

    Evolution of Escherichia coli to 42 °C and Subsequent Genetic Engineering Reveals Adaptive Mechanisms and Novel Mutations.. / Sandberg, Troy E.; Pedersen, Margit; LaCroix, Ryan A.; Ebrahim, Ali; Bonde, Mads; Herrgard, Markus; Palsson, Bernhard; Sommer, Morten; Feist, Adam.

    In: Molecular Biology and Evolution, Vol. 31, No. 10, 2014, p. 2647-2662.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  42. Published
  43. Published
  44. Published

    Facilitating the use of large-scale biological data and tools in the era of translational bioinformatics. / Kouskoumvekaki, Irene; Shublaq, Nour ; Brunak, Søren.

    In: Briefings in Bioinformatics, Vol. 15, No. 6, 2014, p. 942-952.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  45. E-pub ahead of print

    Fast Swinnex Filtration (FSF): A fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media. / McCloskey, Douglas; Utrilla, Jose; Naviaux, Robert K.; Palsson, Bernhard O.; Feist, Adam.

    In: Metabolomics, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  46. E-pub ahead of print

    ‘Forcing the issue’ – Aromatic tuning facilitates stimulus-independent modulation of a two-component signaling circuit. / Nørholm, Morten; von Heijne, Gunnar; Draheim, Roger R.

    In: A C S Synthetic Biology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  47. Published

    Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm, GEM-Path. / Campodonico, Miguel A.; Andrews, Barbara A.; Asenjo, Juan A.; Palsson, Bernhard; Feist, Adam.

    In: Metabolic Engineering, Vol. 25, 2014, p. 140-158.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  48. Published

    Genetically engineered yeast. / Borodina, Irina (Inventor); Kildegaard, Kanchana Rueksomtawin (Inventor); Förster, Jochen (Inventor); Öberg, Fredrik (Inventor).

    IPC No.: C12N15/52. Patent No.: WO2014057036. Apr 17, 2014.

    Publication: ResearchPatent – Annual report year: 2014

  49. Published

    Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae. / Liu, Lifang; Feizi, Amir; Osterlund, Tobias; Hjort, Carsten; Nielsen, Jens.

    In: B M C Systems Biology, Vol. 8, No. 73, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  50. Published

    Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states. / Cho, Byung-Kwan; Kim, Donghyuk; Knight, Eric M.; Zengler, Karsten; Palsson, Bernhard.

    In: Journal of Biology (Online), Vol. 12, No. 4, 4, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  51. Published
  52. Published

    High-throughput screening for industrial enzyme production hosts by droplet microfluidics. / Sjostrom, Staffan L.; Bai, Yunpeng; Huang, Mingtao; Liu, Zihe; Nielsen, Jens; Jönsson, Håkan; Svahn, Helene Andersson.

    In: Lab On a Chip, Vol. 14, No. 4, 2014, p. 806-813.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  53. Published

    How to Fight Back Against Antibiotic Resistance. / Dantas, Gautam; Sommer, Morten.

    In: American Scientist, Vol. 102, No. 1, 2014, p. 42-51.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  54. Published

    Human Intestinal Cells Modulate Conjugational Transfer of Multidrug Resistance Plasmids between Clinical Escherichia coli Isolates.. / Machado, Ana Manuel; Sommer, Morten.

    In: P L o S One, Vol. 9, No. 6, 2014, p. e100739.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  55. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes. / Nielsen, Henrik Bjørn; Almeida, Mathieu; Juncker, Agnieszka; Rasmussen, Simon; Li, Junhua; Sunagawa, Shinichi; Plichta, Damian Rafal; Gautier, Laurent; Pedersen, Anders Gorm; Emmanuelle, Le Chatelier; Pelletier, Eric; Bonde, Ida; Nielsen, Trine; Manichanh, Chaysavanh; Arumugam, Manimozhiyan; Batto, Jean-Michel; dos Santos, Marcelo Bertalan Quintanilha; Blom, Nikolaj; Borruel, Natalia; Burgdorf, Kristoffer S.; Boumezbeur, Fouad; Casellas, Francesc; Doré, Joël; Dworzynski, Piotr; Guarner, Francisco; Hansen, Torben; Hildebrand, Falk; Kaas, Rolf Sommer; Kennedy, Sean; Kristiansen, Karsten; Kultima, Jens Roat; Léonard, Pierre; Levenez, Florence; Lund, Ole; Moumen, Bouziane; Denis, Le Paslier; Pons, Nicolas; Pedersen, Oluf; Prifti, Edi; Qin, Junjie; Raes, Jeroen; Sørensen, Søren; Tap, Julien; Tims, Sebastian; Ussery, David; Yamada, Takuji; Renault, Pierre; Sicheritz-Pontén, Thomas; Bork, Peer; Wang, Jun; Brunak, Søren; Ehrlich, S. Dusko.

    In: Nature Biotechnology, Vol. 32, No. 8, 2014, p. 822-828.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  56. Published

    Identification of Bacterial Small RNAs by RNA Sequencing. / Gómez Lozano, María; Marvig, Rasmus Lykke; Molin, Søren; Long, Katherine.

    Pseudomonas Methods and Protocols. ed. / Alain Filloux; Juan-Luis Ramos. Springer Science+Business Media B.V., 2014. p. 433-456 (Methods in Molecular Biology, Vol. 1149).

    Publication: Research - peer-reviewBook chapter – Annual report year: 2014

  57. Published

    Identification of genes specifically required for the anaerobic metabolism of benzene in Geobacter metallireducens. / Zhang, Tian; Tremblay, Pier-Luc; Chaurasia, Akhilesh Kumar; Smith, Jessica A.; Bain, Timothy S.

    In: Frontiers in Microbiology, Vol. 5, 245, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  58. Published

    Impact of protein uptake and degradation on recombinant protein secretion in yeast. / Tyo, Keith E. J.; Liu, Zihe; Magnusson, Ylva; Petranovic, Dina; Nielsen, Jens.

    In: Applied Microbiology and Biotechnology, Vol. 98, No. 16, 2014, p. 7149-7159.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  59. Published

    Improved Production of a Heterologous Amylase in Saccharomyces cerevisiae by Inverse Metabolic Engineering. / Liu, Zihe; Liu, Lifang; Osterlund, Tobias; Hou, Jin; Huang, Mingtao; Fagerberg, Linn; Petranovic, Dina; Uhlén, Mathias; Nielsen, Jens.

    In: APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 80, No. 17, 2014, p. 5542-5550.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  60. Published

    Improving biotech education through gamified laboratory simulations. / Bonde, Mads; Makransky, Guido; Wandall, Jakob; Larsen, Mette Voldby; Morsing, Mikkel; Jarmer, Hanne Østergaard; Sommer, Morten.

    In: Nature Biotechnology, Vol. 32, No. 7, 2014, p. 694-697.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  61. Published

    Increasing prevalence of group B streptococcal infection among pregnant women. / Petersen, Kathrine Birch; Johansen, Helle Krogh; Rosthoj, Susanne; Krebs, Lone; Pinborg, Anja; Hedegaard, Morten.

    In: Danish Medical Bulletin (Online), Vol. 61, No. 9, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  62. Published

    In silico tools for the analysis of antibiotic biosynthetic pathways.. / Weber, Tilmann.

    In: International Journal of Medical Microbiology, Vol. 304, 2014, p. 230-235.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  63. Published

    Library sequencing strategies for comparative analysis of stress resistance mechanisms in Escherichia coli strains. / Lennen, Rebecca; Bonde, Ida; Koza, Anna; Herrgard, Markus.

    In: New Biotechnology, Vol. 31, 2014, p. S86.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  64. Published

    Liquid chromatography/mass spectrometry analysis of branched fructans produced in vitro with C-13-labeled substrates. / Verspreet, Joran; Hansen, Anders Holmgaard; Dornez, Emmie; Delcour, Jan A.; Harrison, Scott James; Courtin, Christophe M.

    In: Rapid Communications in Mass Spectrometry, Vol. 28, No. 20, 2014, p. 2191-2200.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  65. Published

    Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis. / Jiricny, Natalie; Molin, Søren; Foster, Kevin; Diggle, Stephen P.; Scanlan, Pauline D.; Ghoul, Melanie; Johansen, Helle Krogh; Santorelli, Lorenzo A.; Popat, Roman; West, Stuart A.; Griffin, Ashleigh S.

    In: P L o S One, Vol. 9, No. 1, 2014, p. Article No.: e83124.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  66. Published

    Management of the endoplasmic reticulum stress by activation of the heat shock response in yeast. / Hou, Jin; Tang, Hongting; Liu, Zihe; Østerlund, Tobias; Nielsen, Jens; Petranovic, Dina.

    In: F E M S Immunology and Medical Microbiology, Vol. 14, No. 3, 2014, p. 481-494.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  67. Published

    Metabolic impact of an NADH-producing glucose-6-phosphate dehydrogenase in Escherichia coli.. / Olavarria, K.; De Ingeniis, J.; Zielinski, D. C.; Fuentealba, M.; Muñoz, R.; McCloskey, D.; Feist, Adam; Cabrera, R.

    In: Microbiology, Vol. 160, No. Pt 12, 2014, p. 2780-2793.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  68. Published

    Metagenomic Systems Biology of the Human Microbiome. / Bonde, Ida; Nielsen, Henrik Bjørn (Supervisor); Sicheritz-Pontén, Thomas (Main supervisor).

    Technical University of Denmark, 2014. 153 p.

    Publication: ResearchPh.D. thesis – Annual report year: 2014

  69. E-pub ahead of print

    Microbial synthesis of the forskolin precursor manoyl oxide in enantiomerically pure form. / Nielsen, Morten Thrane; Ranberg, Johan Andersen; Christensen, Ulla; Christensen, Hanne Bjerre; Harrison, Scott James; Olsen, Carl Erik; Hamberger, Björn; Møller, Birger Lindberg; Nørholm, Morten.

    In: Applied and Environmental Microbiology, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  70. Published

    Microbiology: Barriers to the spread of resistance. / Sommer, Morten.

    In: Nature, Vol. 509, 2014, p. 567–568.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  71. Published

    Minimal metabolic pathway structure is consistent with associated biomolecular interactions. / Bordbar, Aarash; Nagarajan, Harish; Lewis, Nathan E.; Latif, Haythem; Ebrahim, Ali; Federowicz, Stephen; Schellenberger, Jan; Palsson, Bernhard.

    In: Molecular Systems Biology, Vol. 10, No. 7, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  72. Published

    MODEST: a web-based design tool for oligonucleotide-mediated genome engineering and recombineering. / Bonde, Mads; Klausen, Michael S.; Anderson, Mads Valdemar; Nilsson Wallin, Annika; Wang, Harris H.; Sommer, Morten.

    In: Nucleic Acids Research, Vol. 12, No. W1, 2014, p. W408-W415.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  73. Published

    Multiple chromosomal gene integration for production of pharmaceutical proteins in S. cerevisiae. / Jensen, Malene; Mortensen, Uffe Hasbro; Gunnarsson, Nina; Strucko, Tomas; Baron, Line Due.

    In: New Biotechnology, Vol. 31, No. Supplement, 2014, p. S192.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  74. Published
  75. Published

    Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae. / King, Zachary A.; Feist, Adam.

    In: Metabolic Engineering, Vol. 24, 2014, p. 117-128.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  76. Published

    Physiological characterization of the high malic acid-producing Aspergillus oryzae strain 2103a-68. / Knuf, Christoph; Nookaew, Intawat; Remmers, Ilse; Khoomrung, Sakda; Brown, Stephen; Berry, Alan; Nielsen, Jens.

    In: Applied Microbiology and Biotechnology, Vol. 98, No. 8, 2014, p. 3517-3527.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  77. Published

    P-Link: A method for generating multicomponent cytochrome P450 fusions with variable linker length. / Belsare, Ketaki D.; Ruff, Anna Joelle; Martinez, Ronny; Shivange, Amol V.; Mundhada, Hemanshu; Holtmann, Dirk; Schrader, Jens; Schwaneberg, Ulrich.

    In: BioTechniques, Vol. 57, No. 1, 2014, p. 13-20.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  78. Published

    Prediction of resistance development against drug combinations by collateral responses to component drugs.. / Munck, Christian; Gumpert, Heidi; Nilsson Wallin, Annika; Wang, Harris H.; Sommer, Morten.

    In: Science Translational Medicine, Vol. 6, No. 262, 262ra156 , 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  79. Published

    Protein network reconstruction of CHO cell secretory pathway. / Lund, Anne Mathilde; Kaas, Christian Schrøder; Kildegaard, Helene Faustrup; Kristensen, Claus; Andersen, Mikael Rørdam.

    2014. Poster session presented at CHOgenome workshop, Vienna, Austria.

    Publication: Research - peer-reviewPoster – Annual report year: 2014

  80. Published

    Putting computational modeling at the fingertips of bench biologists. / Sonnenschein, Nikolaus; Herrgard, Markus.

    2014. Poster session presented at 2nd EMBO Conference on Visualizing Biological Data, Heidelberg, Germany.

    Publication: Research - peer-reviewPoster – Annual report year: 2014

  81. E-pub ahead of print

    Recent applications of synthetic biology tools for yeast metabolic engineering. / Jensen, Michael Krogh; Keasling, Jay.

    In: FEMS Yeast Research, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  82. Published

    Reconstruction and modeling protein translocation and compartmentalization in Escherichia coli at the genome-scale. / Liu, Joanne K.; O’Brien, Edward J.; Lerman, Joshua A.; Zengler, Karsten; Palsson, Bernhard; Feist, Adam.

    In: BMC Systems Biology, Vol. 8, No. 1, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  83. Published

    Reprogramming Acyl Carrier Protein Interactions of an Acyl-CoA Promiscuous trans-Acyltransferase. / Ye, Zhixia; Musiol-Kroll, Ewa Maria; Weber, Tilmann; Williams, Gavin J. .

    In: Chemistry & Biology, Vol. 21, 2014, p. 636-646.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  84. Published

    Secreted single‐stranded DNA is involved in the initial phase of biofilm formation by Neisseria gonorrhoeae. / Zweig, Maria; Schork, Sabine; Koerdt, Andrea; Siewering, Katja; Sternberg, Claus; Thormann, Kai; Albers, Sonja‐Verena; Molin, Søren; Does, Chris, van der.

    In: Environmental Microbiology, Vol. 16, No. 4, 2014, p. 1040-1052.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  85. Published

    Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore. / Zagrobelny, Mika; Olsen, Carl Erik; Pentzold, Stefan; Fürstenberg-Hägg, Joel; Jørgensen, Kirsten; Bak, Søren; Møller, Birger Lindberg; Motawia, Mohammed Saddik.

    In: Insect Biochemistry and Molecular Biology, Vol. 44, 2014, p. 44-53.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  86. E-pub ahead of print
  87. Published

    Sustainable strategies for treatment of bacterial infections. / Molin, Søren.

    Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby : Technical University of Denmark, 2014.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2014

  88. Published

    Systematic Evaluation of Methods for Integration of Transcriptomic Data into Constraint-Based Models of Metabolism.. / Machado, Daniel; Herrgard, Markus.

    In: P L o S Computational Biology, Vol. 10, No. 4, e1003580, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  89. Published

    Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites. / Hwang, Kyu-Sang; Kim, Hyun Uk; Charusanti, Pep; Palsson, Bernhard; Yup Lee, Sang.

    In: Biotechnology Advances, Vol. 32, No. 2, 2014, p. 255-268.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  90. Published

    The astaxanthin dideoxyglycoside biosynthesis pathway in Sphingomonas sp. PB304. / Kim, Se Hyeuk; Kim, Jin Ho; Lee, Bun Yeol; Lee, Pyung Cheon.

    In: Applied Microbiology and Biotechnology, Vol. 98, No. 24, 2014, p. 9993-10003.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  91. Published

    The future of genome-scale modeling of yeast through integration of a transcriptional regulatory network. / Liu, Guodong; Marras, Antonio; Nielsen, Jens.

    In: Quantitative Biology, Vol. 2, No. 1, 2014, p. 30-46.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  92. Published

    The GalNAc-type O-Glycoproteome of CHO Cells Characterized by the SimpleCell Strategy. / Zhang, Yang; Halim, Adnan; Narimatsu, Yoshiki; Jitendra Joshi, Hiren; Steentoft, Catharina; Gram Schjoldager, Katrine Ter-Borch; Alder Schulz, Morten; Sealover, Natalie R.; Kayser, Kevin J.; Paul Bennett, Eric; Levery, Steven B.; Vakhrushev, Sergey Y.; Clausen, Henrik.

    In: Molecular and Cellular Proteomics, Vol. 13, No. 12, 2014, p. 3224-3235.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  93. Published

    The impact of bioaugmentation on dechlorination kinetics and on microbial dechlorinating communities in subsurface clay till. / Bælum, Jacob; Scheutz, Charlotte; Chambon, Julie Claire Claudia; Jensen, Christine Mosegaard; Brochmann, Rikke P.; Dennis, Philip; Laier, Troels; Broholm, Mette Martina; Bjerg, Poul Løgstrup; Binning, Philip John; Jacobsen, Carsten.

    In: Environmental Pollution, Vol. 186, 2014, p. 149-157.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  94. Published

    Toward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectives. / Kaas, Christian Schrøder; Fan, Yuzhou; Weilguny, Dietmar; Kristensen, Claus; Kildegaard, Helene Faustrup; Andersen, Mikael Rørdam.

    In: Pharmaceutical Bioprocessing, Vol. 2, No. 5, 2014, p. 437-448.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  95. Published

    Trash to treasure: Production of biofuels and commodity chemicals via syngas fermenting microorganisms. / Latif, Haythem; Zeidan, Ahmad; Nielsen, Alex Toftgaard; Zengler, Karsten.

    In: Current Opinion in Biotechnology, Vol. 27, 2014, p. 79-87.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  96. Published

    Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. / Raghavan, Maanasa; Skoglund, Pontus; Graf, Kelly E.; Metspalu, Mait; Albrechtsen, Anders; Moltke, Ida; Rasmussen, Simon; Stafford jr., Thomas; Orlando, Ludovic Antoine Alexandre; Metspalu, Ene; Karmin, Monika; Tambets, Kristiina; Rootsi, Siiri; Mägi, Reedik; Campos, Paula; Balanovska, Elena; Balanovsky, Oleg; Khusnutdinova, Elza; Litvinov, Sergey; Osipova, Ludmila P; Fedorova, Sardana A; Voevoda, Mikhail I; Degiorgio, Michael; Sicheritz-Pontén, Thomas; Brunak, Søren; Demeshchenko, Svetlana; Kivisild, Toomas; Villems, Richard; Nielsen, Rasmus; Jakobsson, Mattias; Willerslev, Eske.

    In: Nature, Vol. 505, No. 7481, 2014, p. 87–91.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  97. 2013
  98. Published
  99. Published

    Adaptively evolved yeast mutants on galactose show trade-offs in carbon utilization on glucose. / Hong, Kuk-Ki; Nielsen, Jens.

    In: Metabolic Engineering, Vol. 16, No. 1, 2013, p. 78-86.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  100. Published

    Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks. / Chen, Yun; Nielsen, Jens.

    In: Current Opinion in Biotechnology, Vol. 24, No. 6, 2013, p. 965-972.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  101. Published

    Amphipol trapping of a functional CYP system. / Laursen, Tomas; Naur, Peter; Møller, Birger Lindberg.

    In: Biotechnology and Applied Biochemistry, Vol. 60, No. 1, 2013, p. 119-127.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  102. Published

    Anaerobic α-Amylase Production and Secretion with Fumarate as the Final Electron Acceptor in Saccharomyces cerevisiae. / Liu, Zihe; Österlund, Tobias; Hou, Jin; Petranovic, Dina; Nielsen, Jens.

    In: Applied and Environmental Microbiology, Vol. 79, No. 9, 2013, p. 2962-2967.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  103. Published

    A validated system for ligation-free USER™ -based assembly of expression vectors for mammalian cell engineering. / Lund, Anne Mathilde; Kildegaard, Helene Faustrup; Hansen, Bjarne Gram; Holm, Dorte Koefoed; Andersen, Mikael Rørdam; Mortensen, Uffe Hasbro.

    2013. Poster session presented at 23rd ESACT meeting, Lille, France.

    Publication: Research - peer-reviewPoster – Annual report year: 2013

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