Innate Immunology

  1. 2012
  2. Published

    Expression of Innate Immune Response Genes in Liver and Three Types of Adipose Tissue in Cloned Pigs. / Højbøge, Tina Rødgaard; Skovgaard, Kerstin; Stagsted, Jan; Heegaard, Peter M. H.

    In: Cellular Reprogramming, Vol. 14, No. 5, 2012, p. 407-417.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  3. Published

    Ingen vil betale for forsikringen. / Heegaard, Peter M. H.; Enøe, Claes; Jungersen, Gregers.

    In: Politiken. 2012 ; (13. februar), 01 January 2012. p. 5.

    Publication: CommunicationNewspaper article – Annual report year: 2012

  4. Published

    Local osteogenic expression of cyclooxygenase-2 and systemic response in porcine models of osteomyelitis. / Johansen, Louise K.; Iburg, Tine M.; Nielsen, Ole L.; Leifsson, Páll S.; Dahl-Petersen, Kirstin; Koch, Janne; Frees, Dorte; Aalbæk, Bent; Heegaard, Peter M.H.; Jensen, Henrik E.

    In: Prostaglandins & Other Lipid Mediators, Vol. 97, No. 3-4, 2012, p. 103-108.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  5. Published
  6. Published

    The Impact of Staphylococcus Aureus Concentration on the Development of Pulmonary Lesions and Cytokine Expression After Intravenous Inoculation of Pigs. / Sørensen, K. E.; Skovgaard, Kerstin; Heegaard, Peter M. H.; Jensen, H. E.; Nielsen, O. L. ; Leifsson, P. S.; Olsen, H. G.; Aalbaek, B.; Kristensen, A. T.; Kjelgaard-Hansen, M.; Wiinberg, B.; Iburg, T. M.

    In: Veterinary Pathology, Vol. 49, No. 6, 2012, p. 950-962.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  7. 2011
  8. Published

    Acute phase protein response during acute ruminal acidosis in cattle. / Danscher, A. M.; Thoefner, M. B.; Heegaard, Peter M. H.; Ekstrøm, C. T.; Jacobsen, S.

    In: Livestock Science, Vol. 135, No. 1, 2011, p. 62-69.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  9. Published

    Adjuvants and delivery systems in veterinary vaccinology: current state and future developments. / Heegaard, Peter M. H.; Dedieu, Laurence; Johnson, Nicholas; Potier, Marie-Frédérique Le; Mockey, Michael; Mutinelli, Franco; Vahlenkamp, Thomas; Vascellari, Marta; Sørensen, Nanna Skall.

    In: Archives of Virology, Vol. 156, No. 2, 2011, p. 183-202.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  10. Published
  11. Published

    Enhancement of Muramyldipeptide (MDP) Immunostimulatory Activity by Controlled Multimerization on Dendrimers. / Sørensen, Nanna Skall; Boas, Ulrik; Heegaard, Peter M. H.

    In: Macromolecular Bioscience, Vol. 11, No. 11, 2011, p. 1484-1490.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  12. Published

    Fetal lipopolysaccharide exposure modulates diet-dependent gut maturation and sensitivity to necrotising enterocolitis in pre-term pigs. / Cilieborg, Malene Skovsted; Schmidt, Mette; Skovgaard, Kerstin; Boye, Mette; Weber, Nicolai R.; Heegaard, Peter M. H.; Burrin, Douglas. G.; Sangild, Per T.

    In: British Journal of Nutrition, Vol. 106, No. 6, 2011, p. 852-861.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  13. Published

    Host Response to Porcine Strains of Escherichia coli in a Novel Pyelonephritis Model. / Isling, L.K.; Aalbæk, B.; Birck, M.M.; Heegaard, Peter M. H.; Leifsson, P.S.

    In: Journal of Comparative Pathology, Vol. 144, No. 4, 2011, p. 257-268.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  14. Published

    Infection-induced coronary dysfunction and systemic inflammation in piglets are dampened in hypercholesterolemic milieu. / Birck, Malene M.; Pesonen, Erkki; Odermarsky, Michal; Hansen, Axel K.; Persson, Kenneth; Frikke-Schmidt, Henriette; Heegaard, Peter M. H.; Liuba, Petru.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 300, No. 5, 2011, p. H1595-H1601.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  15. Published

    MicroRNA expression in lung tissue and blood isolated from pigs suffering from bacterial pneumonia. / Skovgaard, Kerstin; Wendt, Karin Tarp; Heegaard, Peter M. H.

    2011. Abstract from International qPCR Symposium & Exhibition, Vienna. Austria, .

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2011

  16. Published

    Optimal combinations of acute phase proteins for detecting infectious disease in pigs. / Heegaard, Peter M. H.; Stockmarr, Anders; Piñeiro, Matilde; Carpintero, Rakel; Lampreave, Fermin; Campbell, Fiona M; Eckersall, P David; Toussaint, Mathilda JM; Gruys, Erik; Sørensen, Nanna Skall.

    In: Veterinary Research, Vol. 42, No. 1, 2011, p. 50.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  17. Published

    Pathology, Tissue Metalloproteinase Transcription and Haptoglobin Responses in Mice after Experimental Challenge with Different Isolates of Pasteurella multocida Obtained from Cases of Porcine Pneumonia. / Pors, S. E.; Chadfield, M. S.; Sørensen, D. B.; Offenberg, H.; Heegaard, Peter M. H.; Bisgaard, M.; Jensen, H. E.

    In: Journal of Comparative Pathology, Vol. 145, No. 2-3, 2011, p. 251-260.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  18. Published
  19. Published
  20. Published

    Structural gene variants in the porcine mannose-binding lectin 1 (MBL1) gene are associated with low serum MBL-A concentrations. / Juul-Madsen, Helle R.; Kjærup, Rikke M.; Toft, Charlotte; Henryon, Mark; Heegaard, Peter M. H.; Berg, Peer; Dalgaard, Tina S.

    In: Immunogenetics, Vol. 63, No. 5, 2011, p. 309-317.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  21. Published

    Transcriptional profiling at different sites in lungs of pigs during acute bacterial respiratory infection. / Mortensen, Shila; Skovgaard, Kerstin; Hedegaard, Jakob; Bendixen, Christian; Heegaard, Peter M. H.

    In: Innate Immunity, Vol. 17, No. 1, 2011, p. 41-53.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  22. Published

    Transition from parenteral to enteral nutrition induces immediate diet-dependent gut histological and immunological responses in preterm neonates. / Siggers, Jayda; Sangild, Per T.; Jensen, Tim Kåre; Siggers, Richard H.; Skovgaard, Kerstin; Støy, Ann Cathrine Findal; Jensen, Bent B.; Thymann, Thomas; Bering, Stine B.; Boye, Mette.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 301, No. 3, 2011, p. G435-G445.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  23. 2010
  24. Published

    A live oral Lawsonia intracellularis vaccine does not result in protective immunity comparable to that of a virulent strain. / Hvass, Henriette Cordes; Riber, Ulla; Ståhl, Marie; Jensen, Tim Kåre; Heegaard, Peter M. H.; Jungersen, Gregers.

    2010. Abstract from Vaccine and ISV Annual Global Congress, Vienna, Astria, .

    Publication: ResearchConference abstract for conference – Annual report year: 2010

  25. Published

    Brief report: biomarkers of aortic vascular prosthetic graft infection in a porcine model with Staphylococcus aureus. / Langerhuus, S. N.; Tønnesen, E. K.; Jensen, K. H.; Damgaard, B. M.; Heegaard, Peter M. H.; Halekoh, U.; Lauridsen, C.

    In: European Journal of Clinical Microbiology & Infectious Diseases, Vol. 29, No. 11, 2010, p. 1453-1456.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  26. Published

    Certain dietary carbohydrates promote Listeria infection in a guinea pig model, while others prevent it. / Ebersbach, Tine; Jørgensen, Julie Boeck; Heegaard, Peter M. H.; Lahtinen, Sampo J.; Ouwehand, Arthur C.; Poulsen, Morten; Frokiær, Hanne; Licht, Tine Rask.

    In: International Journal of Food Microbiology, Vol. 140, No. 2-3, 2010, p. 218-224.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  27. Published

    Cytokine and acute phase protein mRNA expression in liver tissue from pigs with severe sepsis caused by intravenous inoculation of Staphylococcus aureus. / Nielsen, Ole Lerberg; Olsen, Helle Gerda; Iburg, Tine; Jensen, Henrik Elvang; Leifsson, Páll Skuli; Agerholm, Jørgen Steen; Kjelgaard-Hansen, Mads; Wiinberg, Bo; Aalbæk, Bent; Heegaard, Peter M. H.; Skovgaard, Kerstin.

    2010 Annual Meeting SLB & IEIIS: Abstracts. 2010.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2011

  28. Published

    Dendrimers for Vaccine and Immunostimulatory Uses : A Review. / Heegaard, Peter M. H.; Boas, Ulrik; Sørensen, Nanna Skall.

    In: Bioconjugate Chemistry, Vol. 21, No. 3, 2010, p. 405-418.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  29. Published

    Expression of coding (mRNA) and non-coding (microRNA) RNA in lung tissue and blood isolated from pigs suffering from bacterial pleuropneumonia. / Skovgaard, Kerstin; Schou, Kirstine Klitgaard; Wendt, Karin Tarp; Heegaard, Peter M. H.

    Graduate School of Immunology 5th Annual Meeting: Translational Immunology: from vaccines to immunotherapy. 2010.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2011

  30. Published

    Extraction of mRNA from coagulated horse blood and analysis of inflammation-related cytokine responses to coagulation. / Bovbjerg, Kirsten Katrine Lindegaard; Heegaard, Peter M. H.; EFSA Publication.

    2010 Annual Meeting SLB & IEIIS: Abstracts. 2010.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2011

  31. Published
  32. Published

    Host response to Foot- and Mouth Disease infection in cattle; possible implications for the development of “carriers”.. / Stenfeldt, Carolina; Heegaard, Peter M. H.; Tjørnehøj, Kirsten; Belsham, Graham.

    2010. Poster session presented at 4th Annual Meeting EPIZONE, Saint Malo, France.

    Publication: Research - peer-reviewPoster – Annual report year: 2010

  33. Published

    Host response to Foot- and Mouth Disease infection in cattle; possible implications for the development of “carriers”.. / Stenfeldt, Carolina; Heegaard, Peter M. H.

    2010. Abstract from EPIZONE Theme 5 annual meeting, Copenhagen, .

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2010

  34. Published

    Intravenous inoculation of Staphylococcus aureus in pigs induces severe sepsis as indicated by increased hypercoagulability and hepatic dysfunction. / Leifsson, Pall S.; Iburg, Tine; Jensen, Henrik E.; Agerholm, Jørgen S.; Kjelgaard-Hansen, Mads; Wiinberg, Bo; Heegaard, Peter M. H.; Astrup, Lærke B.; Olsson, Anna E.; Skov, Mette G.; Aalbæk, Bent; Nielsen, Ole L.

    In: F E M S Microbiology Letters, Vol. 309, No. 2, 2010, p. 208-216.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  35. Published

    Local and disseminated acute phase response during bacterial respiratory infection in pigs. / Skovgaard, Kerstin; Mortensen, Shila; Heegaard, Peter M. H.

    Proceedings of the 8th European Colloquium on Acute Phase Proteins. 2010.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2011

  36. Published

    Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs. / Brookes, Sharon M; Nunez, Alejandor; Choudhury, Bhudipa; Matrosovich, Mikhail; Essen, Stephen C; Clifford, Derek; Slomka, Marek J; Kuntz-Simon, Gaélle; Garcon, Fanny; Nash, Bethany; Hanna, Amanda; Heegaard, Peter M. H.; Queguiner, Stéphane; Bublot, Michel; Garcia, Jaime Maldonado; Gardner, Rebecca; Foni, Emanuela; Loeffen, Willie; Larsen, Lars Erik; Reeth, Kristien Van; Banks, Jill; Irvine, Richard M.; Brown, Ian H.

    In: P L o S One, Vol. 5, No. 2, 2010, p. 1 - 9.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  37. Published

    The porcine systemic response to pleuropneumonia studied by transcriptional profiling of liver and tracheobronchial lung lymph nodes using multiplexed mRNA-Seq. / Hedegaard, Jakob; Schou, Kirstine Klitgaard; Skovgaard, Kerstin; Zhan, Bujie; Panitz, Frank; Hornshøj, Henrik; Heegaard, Peter M. H.; Angen, Øystein; Boye, Mette; Bendixen, Christian.

    Proceedings of the 32nd Conference for the International Society for Animal Genetics. 2010.

    Publication: Research - peer-reviewConference abstract in proceedings – Annual report year: 2011

  38. 2009
  39. Published

    Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs. / Thymann, Thomas; Møller, Hanne; Stoll, Barbara; Støy, Ann Cathrine Findal; Buddington, Randal K.; Bering, Stine B.; Jensen, Bent B.; Olutoye, Oluyinka O.; Siggers, Richard H.; Mølbak, Lars; Sangild, Per T.; Burrin, Douglas G.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 297, No. 6, 12.2009, p. G1115-G1125.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  40. Published

    Addition of casein to a whey-based formula has limited effects on gut function in preterm pigs. / Thymann, T; Møller, H K; Støy, Ann Cathrine Findal; Bering, S; Mølbak, Lars; Burrin, D; Sangild, P. T.

    In: Acta Paediatrica, Vol. 98, No. Suppl. 460, 2009, p. 226-226.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  41. Published

    A pig model of acute Staphylococcus aureus induced pyemia. / Nielsen, O. L.; Iburg, T.; Aalbæk, B.; Leifsson, P. S.; Agerholm, J. S.; Heegaard, Peter M. H.; Boye, Mette; Simon, S.; Jensen, K. B.; Christensen, S.; Melsen, K.; Bak, A. K.; Backman, E. R.; Jørgensen, M. H.; Groegler, D.K.; Jensen, A. L.; Kjelgaard-Hansen, M.; Jensen, H. E.

    In: Acta Veterinaria Scandinavica (Online Edition), Vol. 51, 2009, p. 14.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  42. Published

    A robust quantitative solid phase immunoassay for the acute phase protein C-reactive protein (CRP) based on cytidine 5 '-diphosphocholine coupled dendrimers. / Heegaard, Peter M. H.; Pedersen, H. G.; Jensen, A. L.; Boas, Ulrik.

    In: Journal of Immunological Methods, Vol. 343, No. 2, 2009, p. 112-118.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  43. Published

    A two-locus DNA sequence database for typing plant and human pathogens within the Fusarium oxysporum species complex.. / O'Donnell, Kerry; Gueidan, C; Sink, S; Johnston, PR; Crous, PV; Glenn, A; Riley, R; Zitomer, NC; Colyer, P; Waalwijk, C; Lee, T; Moretti, AS; Kang, S; Kim, HS; Geiser, DM; Juba, HJ; Baayen, RP; Cromey, PW; Bithell, A; Sutton, RR; Skovgaard, Kerstin; Ploetz, R; Kistler, H; Sarver, BA.

    In: Fungal Genetics and Biology, Vol. 46, No. 12, 2009, p. 936-948.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  44. Published

    Backbone Amide Linker in Solid-Phase Synthesis. / Boas, Ulrik; Brask, Jesper; Jensen, K. J.

    In: Chemical Reviews, Vol. 109, No. 5, 2009, p. 2092-2118.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  45. Published

    Bovine colostrum against gut inflammatory lesions in preterm pigs. / Støy, Ann Cathrine Findal; Thymann, T.; Stoll, B; Sangild, P.

    In: Acta Paediatrica, Vol. 98, No. Suppl. 460, 2009, p. 226-226.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  46. Published

    Dendrimer based vaccine adjuvants. / Heegaard, Peter M. H.; Boas, Ulrik; Sørensen, Nanna Skall.

    Polymeric Micelles and Related Nano-delivery Systems. Kentus Book Publishers, 2009.

    Publication: Research - peer-reviewBook chapter – Annual report year: 2009

  47. Published

    Fremstilling af biologisk aktive biomolekyler fra spildprodukter. / Heegaard, Peter M. H.; Lihme, Allan.

    In: Dansk Kemi, Vol. 90, No. 9, 2009, p. 14 - 17.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  48. Published

    Identification of Acute Phase Proteins and Assays Applicable in Nondomesticated Mammals. / Bertelsen, M. F.; Kjelgaard-Hansen, M.; Grøndahl, C.; Heegaard, Peter M. H.; Jacobsen, S.

    In: Journal of Zoo and Wildlife Medicine, Vol. 40, No. 1, 2009, p. 199-203.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  49. Published

    IMMUNOSTIMULATORY PROPERTIES OF DENDRIMERS MULTIVALENTLY PRESENTING MURAMYLDIPEPTIDE. / Sørensen, Nanna Skall (Author); Boas, Ulrik (Author); Heegaard, Peter M. H. (Author).

    2009. 2nd European Congress of Immunology, Berlin, Germany, 13/09/09.

    Publication: ResearchSound/Visual production (digital) – Annual report year: 2009

  50. Published

    Localization of disease-related PrP in Danish patients with different subtypes of prion disease. / Bergström, A. L.; Heegaard, Peter M. H.; Dyrbye, H.; Lind, Peter; Laursen, H.

    In: Clinical Neuropathology, Vol. 28, No. 5, 2009, p. 321 - 332.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  51. Published

    New-generation vaccines : Combining immunology with oganic chemistry and bioinformatics in engineering challanges. / Heegaard, Peter M. H.; Lund, Ole.

    Engineering challenges: energy, climate change & health. Kgs.Lyngby : Technical University of Denmark, 2009. p. 210-221 (DTU research series).

    Publication: ResearchBook chapter – Annual report year: 2009

  52. Published

    PORCINE CYTOKINE RESPONSES TO PAMP-STRUCTURES IN VITRO. : KINETICS COMPARING EXPRESSION ON MRNA AND PROTEIN LEVEL. / Sørensen, Nanna Skall; Skovgaard, Kerstin; Vorsholt, Henriette; Heegaard, Peter M. H.

    2009. Abstract from 3rd European Veterinary Immunology Workshop, Berlin, Germany.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2009

  53. Published

    Preterm birth reduces the adaptation to intestinal resection in newborn pigs. / Sangild, P.T.; Thymann, T.; Boving, L.A.; Støy, Ann Cathrine Findal; Lund, P.; Jeppesen, P.B.; Sigalet, D.L.; Qvist, N.

    In: Acta Paediatrica, Vol. 58, No. Suppl. 460, 2009, p. 50-51.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  54. Published

    Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs. / Skovgaard, Kerstin; Mortensen, Shila; Boye, Mette; Wendt, Karin Tarp; Campbell, F. M.; Eckersall, P. D.; Heegaard, Peter M. H.

    In: Veterinary Research, Vol. 40, No. 3, 2009, p. article number: 23.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

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