Enzyme and Protein Chemistry
Organisation profile

About EPC
Enzyme and Protein Chemistry (EPC) is an international group where interchange of competences and experience provides a fertile basis for research and education. The expertise of the group members range from protein biochemistry, carbohydrate biochemistry, molecular biology, microbiology and plant biochemistry.
The main activities of EPC are related to food and raw materials for food, but the methods and main strategies are relevant in relation to various biotechnological issues. The aim is to explain the molecular mechanisms and interactions relevant for functionality and quality of foodstuffs and raw materials and to identify the biochemical mechanisms connected to health promoting and nutrition related effects of food.
EPC houses a core facility for amino acid analysis and protein sequencing offering analyses on a commercial basis for DTU, other universities and industry.
Research
Our main research activities are within the field of biochemistry and food, relating raw materials, functional quality and nutrition. The activities are based on expertise in protein biochemistry, biochemical methodology, protein/protein and protein/carbohydrate interactions, protein engineering and proteomics.
EPC runs a technology platform dedicated to advanced proteome analysis. This includes 2-dimensional gel electrophoresis, mass spectrometry for identification and characterisation of proteins separated by two-dimensional gel electrophoresis, as well as of recombinant proteins; differential gel electrophoresis (DIGE) monitored by a Typhoon scanner, image analysis; and surface plasmon resonance, which is used for sensitive measurements of interactions between proteins and other molecules, typically carbohydrates.
A core facility is dedicated to amino acid analysis and protein sequencing.
Education
At EPC you can receive education at several levels starting with basic courses, projects at different stages of the education including thesis and PhD projects. The courses are within the areas biological chemistry, biochemistry, protein chemistry, nutrition and immunology and can be taken in connection with the different degrees offered at DTU.
Contact information
Søltofts Plads, 224
DK-2800, Kgs. Lyngby
Denmark
- Phone: +45 4525 2731
- Fax: +45 4588 6307
Publications
(437)- Published
Recent development of phosphorylases possessing large potential for oligosaccharide synthesis
Publication: Research - peer-review › Journal article – Annual report year: 2013
- Published
In vitro growth of four individual human gut bacteria on oligosaccharides produced by chemoenzymatic synthesis.
Publication: Research - peer-review › Journal article – Annual report year: 2013
- Published
Comparative fermentation of insoluble carbohydrates in an in vitro human feces model spiked with Lactobacillus acidophilus NCFM
Publication: Research - peer-review › Journal article – Annual report year: 2013
Projects
(23)- Completed
Most frequent publishers
Activities
(1)Digested Ara h 1 retains its sensitising capacity in Brown Norway rats
Activity: Lecture and oral contribution
Most frequent journals
Proteomics
ISSNs: 1615-9853
Wiley - V C H Verlag GmbH & Co. KGaA, Germany
FI (2012): 1, ISI indexed (2012): yes
Central database
Journal
F E B S Journal
ISSNs: 1742-464X
Wiley-Blackwell Publishing Ltd., United Kingdom
FI (2012): 1, ISI indexed (2012): yes
Central database
Journal
F E B S Letters
ISSNs: 0014-5793
Elsevier BV, Netherlands
FI (2012): 1, ISI indexed (2012): yes
Central database
Journal
Most downloaded publications
- 1557
Spectroscopic detection of macromolecular interactions focusing on protein-protein interactions in food
Publication: Research › Ph.d. thesis – Annual report year: 2006
downloads - 1021
Proteome analysis of dissected barley seed tissue during germination and radicle elongation : Heterologous expression of barley limit dextrinase inhibitor
Publication: Research › Ph.d. thesis – Annual report year: 2007
downloads - 876
Monoclonal antibody-based Surface Plasmon Resonance sensors for pathogen detection
Publication: Research › Ph.d. thesis – Annual report year: 2007
downloads - 868
Novel Collagen Markers for Early Detection of Bone Metastases in Breast and Prostate Cancer Patients
Publication: Research › Ph.d. thesis – Annual report year: 2010
downloads - 811
Analysis of vaccine : Structure, storage, moisture, and classification by infrared technology
Publication: Research › Ph.d. thesis – Annual report year: 2006
downloads
Latest activities and conferences
ID: 2382

