Department of Systems Biology

  1. 2015
  2. E-pub ahead of print

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways.. / Ninel Hansen, Stine; Westergaard, David ; Borg Houlberg Thomsen, Mathilde; Vistesen, Mette; Nguyen Do, Khoa; Fogh, Louise; Belling, Kirstine C.; Wang, Jun; Yang, Huanming; Gupta, Ramneek; Ditzel, Henrik Jørn; Moreira, José ; Brünner, Nils; Stenvang, Jan; Schrohl, Anne-Sofie.

    In: Tumor Biology, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  3. Accepted

    Acylcarnitine plasma levels suggest incomplete mitochondrial fatty acid oxidation in young, healthy men with low birth weight. / Ribel-Madsen, Amalie; Ribel-Madsen, Rasmus; Brøns, Charlotte; B. Newgard, Christopher; Vaag, Allan; Hellgren, Lars.

    2015. Abstract from 28th Nordic Lipid Symposium, Reykjavik, Iceland.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  4. Published

    Airway Mucosal Immune-suppression in Neonates of Mothers Receiving A(H1N1)pnd09 Vaccination During Pregnancy. / Pedersen, Susanne Brix; Bischoff, Anne L.; Folsgaard, Nilofar V.; Vissing, Nadja H.; Birch, Sune; Bisgaard, Hans .

    In: Pediatric Infectious Disease Journal, Vol. 34, No. 1, 2015, p. 84-90.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  5. Published

    Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation. / Fan, Yuzhou; Jimenez Del Val, Ioscani; Müller, Christian; Wagtberg Sen, Jette; Rasmussen, Søren Kofoed; Kontoravdi, Cleo; Weilguny, Dietmar; Andersen, Mikael Rørdam.

    In: Biotechnology and Bioengineering, Vol. 112, No. 3, 2015, p. 521-535.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  6. Published

    A novel common variant in DCST2 is associated with length in early life and height in adulthood. / van der Valk, Ralf J.P.; Kreiner-Møller, Eskil; Kooijman, Marjolein N.; Guxens, Mònica; Stergiakouli, Evangelia; Sääf, Annika; Bradfield, Jonathan P.; Geller, Frank; Hayes, M. Geoffrey; Cousminer, Diana L.; Bisgaard, Hans; Chawes, Bo; Stokholm, Jakob; Waage, Johannes; Eriksen, Patrick; Sevelsted, Astrid; Melbye, Mads; Feenstra, Bjarke; Pers, Tune Hannes; Bønnelykke, Klaus.

    In: Human Molecular Genetics, Vol. 24, No. 4, 2015, p. 1155-1168.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  7. Published

    Archival Bone Marrow Samples: Suitable for Multiple Biomarker Analysis?. / Lund, Bendik; Najmi, A. Laeya; Wesolowska, Agata; Landsem, Veslemoy M.; Rasmussen, Kirsten K.; Borst, Louise; Gupta, Ramneek; Schmiegelow, Kjeld; Klungland, Helge.

    In: Applied Immunohistochemistry & Molecular Morphology, Vol. 23, No. 1, 2015, p. 71-77.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. Published
  9. Published
  10. Published

    Bioinformatics prediction of swine MHC class I epitopes from Porcine Reproductive and Respiratory Syndrome Virus. / Welner, Simon; Nielsen, Morten; Lund, Ole; Jungersen, Gregers; Larsen, Lars Erik.

    2015. Abstract from Keystone Symposia on Molecular and Cellular Biology: Accelerating life science discovery, Keystone, United States.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  11. Published

    Characterization of Alternaria strains from Argentinean blueberry, tomato, walnut and wheat. / Andersen, Birgitte; Nielsen, Kristian Fog; Fernández Pinto, Virginia; Patriarca, Andrea.

    In: International Journal of Food Microbiology, Vol. 196, 2015, p. 1-10.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  12. Published
  13. Published
  14. Published

    CTX-M-1 β-lactamase expression in Escherichia coli is dependent on cefotaxime concentration, growth phase and gene location.. / Kjeldsen, Thea S. B.; Overgaard, Martin; Nielsen, Søren S.; Bortolaia, Valeria; Jelsbak, Lotte; Sommer, Morten Otto Alexander; Guardabassi, Luca; Olsen, John E.

    In: Journal of Antimicrobial Chemotherapy, Vol. 70, No. 1, 2015, p. 62-70.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  15. E-pub ahead of print

    Current state of genome-scale modeling in filamentous fungi. / Brandl, Julian; Andersen, Mikael Rørdam.

    In: Biotechnology Letters, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  16. In press

    Dereplication-guided isolation of depsides thielavins S–T and lecanorins D–F from the endophytic fungus Setophoma sp.. / Soman De Medeiros, Lívia; Abreu, Lucas M.; Nielsen, Anita; Ingmer, Hanne; Larsen, Thomas Ostenfeld; Nielsen, Kristian Fog; Rodrigues-Filho, Edson.

    In: Phytochemistry, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  17. Published

    Dynamic single-cell analysis of Saccharomyces cerevisiae under process perturbation: Comparison of different methods for monitoring the intensity of population heterogeneity. / Delvigne, Frank; Baert, Jonathan; Gofflot, Sébastien; Lejeune, Annick; Telek, Samuel; Johanson, Ted; Eliasson Lantz, Anna.

    In: Journal of Chemical Technology and Biotechnology, Vol. 90, No. 2, 2015, p. 314–323.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  18. Published
  19. Published

    Gene expression analysis identifies global gene dosage sensitivity in cancer. / Fehrmann, Rudolf S. N.; Karjalainen, Juha M.; Krajewska, Malgorzata; Westra, Harm-Jan; Maloney, David; Simeonov, Anton; Pers, Tune Hannes; Hirschhorn, Joel N.; Jansen, Ritsert C.; Schultes, Erik A.; van Haagenl, Herman H. H. B. M.; de Vries, Elisabeth G. E.; Meerman, Gerard J. te; Wijmenga, Cisca; van Vugt, Marcel A. T. M.; Franke, Lude.

    In: Nature Genetics, Vol. 47, No. 2, 2015, p. 115-125.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  20. Published

    Genomic Dissection of Travel-Associated Extended-Spectrum-Beta-Lactamase-Producing Salmonella enterica Serovar Typhi Isolates Originating from the Philippines: a One-Off Occurrence or a Threat to Effective Treatment of Typhoid Fever?. / Hendriksen, Rene S.; Leekitcharoenphon, Pimlapas; Mikoleit, Matthew; Jensen, Jacob Dyring; Kaas, Rolf Sommer; Roer, Louise; Joshi, Heena B.; Pornruangmong, Srirat; Pulsrikarn, Chaiwat; Gonzalez-Aviles, Gladys D.; Reuland, E. Ascelijn; Al Naiemi, Nashwan; Wester, Astrid Louise; Aarestrup, Frank Møller; Hasman, Henrik.

    In: Journal of Clinical Microbiology, Vol. 53, No. 2, 2015, p. 20677-680.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  21. Published

    Genomic Signature of Multidrug-Resistant Salmonella enterica Serovar Typhi Isolates Related to a Massive Outbreak in Zambia between 2010 and 2012.. / Hendriksen, Rene S.; Leekitcharoenphon, Pimlapas; Lukjancenko, Oksana; Lukwesa-Musyani, Chileshe; Tambatamba, Bushimbwa; Mwaba, John; Kalonda, Annie; Nakazwe, Ruth; Kwenda, Geoffrey; Jensen, Jacob Dyring; Svendsen, Christina Aaby; Dittmann, Karen K.; Kaas, Rolf Sommer; Cavaco, Lina; Aarestrup, Frank Møller; Hasman, Henrik; Mwansa, James C. L.

    In: Journal of Clinical Microbiology, Vol. 53, No. 1, 2015, p. 262-272.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  22. Published
  23. Published
  24. Published

    Gliadin affects glucose homeostasis and intestinal metagenome in C57BL6 mice fed a high-fat diet. / Zhang, Li; Hansen, Axel Kornerup; Bahl, Martin Iain; Hansen, Camilla Hartmann Friis; Andersen, Daniel; Pedersen, Susanne Brix; Hellgren, Lars; Licht, Tine Rask.

    2015. Abstract from Keystone Symposia - Gut Microbiota Modulation of Host Physiology: The Search for Mechanism, Keystone, Colorado, United States.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  25. Accepted

    Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macroevolution of a double minute chromosome.. / Favero, Francesco; McGranahan, Nicholas; Salm, Maximilian P.; Birkbak, Nicolai Juul; Sanborn, J. Zachary ; Benz, Stephen C. ; Becq, Jennifer; Peden, John F. ; Kingsbury, Zoya ; Grocok, Russell J. ; Eklund, Aron Charles.

    In: Annals of Oncology, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  26. Published

    Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection. / Esaki, Hitokazu; Ewald, David Adrian; Ungar, Benjamin; Rozenblit, Mariya; Zheng, Xiuzhong; Xu, Hui; Estrada, Yeriel D.; Peng, Xiangyu; Mitsui, Hiroshi; Litman, Thomas; Suarez-Farinas, Mayte; Krueger, James G.; Guttman-Yassky, Emma.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 1, 2015, p. 153-163.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  27. Published
  28. Published

    Lactococcus lactis Thioredoxin Reductase Is Sensitive to Light Inactivation. / Björnberg, Olof; Viennet, Thibault; Skjoldager, Nicklas; Curovic, Aida; Nielsen, Kristian Fog; Svensson, Birte; Hagglund, P.

    In: Biochemistry, Vol. 54, No. 8, 2015, p. 1628-1637.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  29. Published
  30. Published

    Metagenomic heterogeneity explains dual immune effects of endotoxins. / Pedersen, Susanne Brix; Eriksen, Carsten; Larsen, Jeppe Madura; Bisgaard, Hans Flinker.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 1, 2015, p. 277-280.

    Publication: Research - peer-reviewComment/debate – Annual report year: 2015

  31. Published

    Microbial Biofilm as a Smart Material. / Garde, Christian; Welch, Martin; Ferkinghoff-Borg, Jesper; Sams, Thomas.

    In: Sensors, Vol. 15, No. 2, 2015, p. 4229-4241.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  32. Published

    Name Changes in Medically Important Fungi and Their Implications for Clinical Practice. / de Hoog, G. Sybren; Chaturvedi, Vishnu; Denning, David W.; Dyer, Paul S.; Frisvad, Jens Christian; Geiser, David; Gräser, Yvonne; Guarro, Josep; Haase, Gerhard; Kwon-Chung, Kyung-Joo; Meis, Jacques F.; Meyer, Wieland; Pitt, John I.; Samson, Robert A.; Taylor, John W.; Tintelnot, Kathrin; Vitale, Roxana G.; Walsh, Thomas J.; Lackner, Michaela.

    In: Journal of Clinical Microbiology, Vol. 53, No. 4, 2015, p. 1056-1062.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  33. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. / Besenbacher, Søren; Liu, Siyang; Gonzalez-Izarzugaza, Jose Maria; Grove, Jakob; Belling, Kirstine C.; Bork-Jensen, Jette; Huang, Shujia; Dam-Als, Thomas; Li, Shengting; Yadav, Rachita; Yadav, Rachita; Rubio García, Arcadio; Lescai, Francesco; Demontis, Ditte ; Rao, Junhua ; Ye, Weijian ; Mailund, Thomas; Friborg, Rune M. ; Pedersen, Christian N. S.; Xu, Ruiqi; Sun, Jihua; Liu, Hao ; Wang, Ou ; Cheng, Xiaofang ; Flores Santa Cruz, David; Rydza, Emil Karol; Rapacki, Kristoffer; Sørensen, John Damm; Chmura, Piotr Jaroslaw; Westergaard, David; Dworzynski, Piotr; Sørensen, Thorkild I. A.; Lund, Ole; Hansen, Torben; Xu, Xun; Li, Ning; Bolund, Lars; Pedersen, Oluf; Eiberg, Hans; Krogh, Anders; Børglum, Anders D.; Brunak, Søren; Kristiansen, Karsten; Schierup, Mikkel H; Jun, Wang; Gupta, Ramneek; Villesen, Palle ; Rasmussen, Simon.

    In: Nature Communications, Vol. 6, 5969, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  34. Published

    Optimering af vandforsyningens moniteringsstrategi ved hjælp af GIS-analyse. / Albrechtsen, Hans-Jørgen (Author); Christensen, Sarah Christine Boesgaard (Author); Grønkjær, Thomas (Author); Kirstein, Jonas (Author); Larsen, Sille Lyster (Author); Rygaard, Martin (Author).

    2015. Dansk Vand Konference 2014, Århus, Denmark, 18/11/14.

    Publication: ResearchSound/Visual production (digital) – Annual report year: 2015

  35. Published

    Physiological and proteome studies of responses to heat stress during grain filling in contrasting wheat cultivars. / Wang, Xiao; Dinler, Burcu Seckin; Vignjevic, Marija; Jacobsen, Susanne; Wollenweber, Bernd .

    In: Plant Science, Vol. 230, 2015, p. 33-50.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  36. Published
  37. Published

    Renal impairment and late toxicity in germ-cell cancer survivors.. / Lauritsen, J.; Mortensen, M. S.; Kier, M. G. G.; Christensen, I. J.; Agerbaek, M.; Gupta, Ramneek; Daugaard, G.

    In: Annals of Oncology, Vol. 26, No. 1, 2015, p. 173-178.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  38. Published
  39. Published
  40. Published

    Silent clusters : speak up!. / Gram, Lone.

    In: Microbial Biotechnology, Vol. 8, No. 1, 2015, p. 13-14.

    Publication: Research - peer-reviewComment/debate – Annual report year: 2015

  41. Published

    SNPsnap: a Web-based tool for identification and annotation of matched SNPs. / Pers, Tune Hannes; Timshel, Pascal; Hirschhorn, Joel N.

    In: Bioinformatics, Vol. 31, No. 3, 2015, p. 418-420.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  42. Published

    Spatio-temporal appearance of α-amylase and limit dextrinase in barley aleurone layer in response to gibberellic acid, abscisic acid and salicylic acid.. / Shahpiri, Azar; Talaei, Nasim; Finnie, Christine.

    In: Journal of the Science of Food and Agriculture, Vol. 95, No. 1, 2015, p. 141-147.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  43. Published

    Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria. / Lau, Clinton K.Y.; Turner, Louise; Jespersen, Jakob S.; Lowe, Edward D. ; Petersen, Bent; Wang, Christian W.; Petersen, Jens E.V.; Lusingu, John; Theander, Thor G.; Lavstsen, Thomas; Higgins, Matthew K.

    In: Cell Host & Microbe, Vol. 17, 2015, p. 118-129.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  44. Published

    Tabhu: tools for antibody humanization.. / Olimpieri, Pier Paolo; Marcatili, Paolo; Tramontano, Anna.

    In: Bioinformatics, Vol. 31, No. 3, 2015, p. 20434-20435.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  45. Published

    Taxonomy, chemodiversity, and chemoconsistency of Aspergillus, Penicillium, and Talaromyces species. / Frisvad, Jens Christian.

    In: Frontiers in Microbiology, Vol. 5, 773, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  46. Published

    The fur Gene as a New Phylogenetic Marker for Vibrionaceae Species Identification. / Machado, Henrique; Gram, Lone.

    In: Applied and Environmental Microbiology, Vol. 81, No. 8, 2015, p. 2745-2752.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  47. Published

    The importance of massspectrometric dereplication in fungal secondary metabolite analysis. / Nielsen, Kristian Fog; Larsen, Thomas Ostenfeld.

    In: Frontiers in Microbiology, Vol. 6, 71, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  48. Published

    Traces of ATCV-1 associated with laboratory component contamination. / Kjartansdóttir, Kristín Rós ; Friis-Nielsen, Jens; Asplund, Maria ; Mollerup, Sarah ; Mourier, Tobias ; Holm Jensen, Randi ; Arn Hansen, Thomas; Rey-Iglesia, Alba ; Raith Richter, Stine ; Alquezar-Planas, David E. ; Olsen, Pernille V. S. ; Vinner, Lasse ; Fridholm, Helena ; Sicheritz-Pontén, Thomas; Nielsen, Lars Peter; Brunak, Søren; Willerslev, Eske; Gonzalez-Izarzugaza, Jose Maria; Hansen, Anders Johannes .

    In: National Academy of Sciences. Proceedings, 2015, p. E925–E926.

    Publication: Research - peer-reviewLetter – Annual report year: 2015

  49. Published

    Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism. / Hao, Qin; Yadav, Rachita; Basse, Astrid L.; Petersen, Sidsel ; Sonne, Si B.; Rasmussen, Simon; Zhu, Qianhua; Lu, Zhike; Wang, Jun; Audouze, Karine Marie Laure; Gupta, Ramneek; Madsen, Lise; Kristiansen, Karsten; Hansen, Jacob B.

    In: Endocrinology and Metabolism, Vol. 308, No. 5, 2015, p. E380-E392.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  50. Published

    Two Lactococcus lactis thioredoxin paralogues play different roles in responses to arsenate and oxidative stress. / Efler, Petr; Kilstrup, Mogens; Johnsen, Stig; Svensson, Birte; Hägglund, Per.

    In: Microbiology, Vol. 161, No. Pt 3, 2015, p. 528-538.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  51. Published
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