Department of Systems Biology

  1. 2014
  2. Published
  3. Published

    A Generally Applicable Translational Strategy Identifies S100A4 as a Candidate Gene in Allergy. / Bruhn, Sören; Fang, Yu; Barrenäs, Fredrik; Gustafsson, Mika; Zhang, Huan; Konstantinell, Aelita; Krönke, Andrea; Sönnichsen, Birte; Bresnick, Anne; Dulyaninova, Natalya; Wang, Hui; Zhao, Yelin; Klingelhöfer, Jörg; Ambartsumian, Noona; Beck, Mette Kristina; Nestor, Colm; Bona, Elsa; Xiang, Zou; Benson, Mikael.

    In: Science Translational Medicine, Vol. 6, No. 218, 2014, p. 20218ra4-218ra4.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  4. Published
  5. Published
  6. Published

    An elevated pro-inflammatory cytokine profile in multiple chemical sensitivity. / Dantoft, Thomas Meinertz; Elberling, J.; Pedersen, Susanne Brix; Szecsi, P.B.; Vesterhauge, S.; Skovbjerg, S.

    In: Psychoneuroendocrinology, Vol. 40, 2014, p. 140-150.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  7. Published
  8. Published

    A novel platform for heterologous gene expression in Trichoderma reesei (Teleomorph Hypocrea jecorina). / Jørgensen, Mikael Skaanning; Skovlund, Dominique Aubert; Johannesen, Pia Francke; Mortensen, Uffe Hasbro.

    In: Microbial Cell Factories, Vol. 13, No. 1, 2014, p. 33.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  9. E-pub ahead of print
  10. Published
  11. Published

    Children with asthma by school age display aberrant immune responses to pathogenic airway bacteria as infants. / Larsen, Jeppe Madura; Pedersen, Susanne Brix; Thysen, Anna Hammerich; Birch, Sune; Rasmussen, Morten Arendt; Bisgaard, Hans Flinker.

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 4, 2014, p. 1008-1013.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  12. Published

    Compass: A hybrid method for clinical and biobank data mining. / Krysiak-Baltyn, Konrad; Petersen, Thomas Nordahl; Audouze, Karine Marie Laure; Jørgensen, Niels; Ängquist, L.; Brunak, Søren.

    In: Journal of Biomedical Informatics, Vol. 47, 2014, p. 160-170.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  13. Published

    Complete Genome Sequence of Border Disease Virus Genotype 3 Strain Gifhorn. / Fahnøe, Ulrik; Höper, Dirk ; Beer, Martin; Rasmussen, Thomas Bruun.

    In: Genome Announcements, Vol. 2, No. 1, e01142-13, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  14. Published

    CoreFlow: A computational platform for integration, analysis and modeling of complex biological data. / Pasculescu, Adrian; Schoof, Erwin; Creixell, Pau; Zheng, Yong; Olhovsky, Marina; Tian, Ruijun; So, Jonathan; Vanderlaan, Rachel D.; Pawson, Tony; Linding, Rune; Colwill, Karen.

    In: Journal of Proteomics, Vol. 100, 2014, p. 167-173.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  15. Published

    Distinct substrate specificities of three glycoside hydrolase family 42 β-galactosidases from Bifidobacterium longum subsp. infantis ATCC 15697. / Viborg, Alexander Holm; Katayama, Takane; Abou Hachem, Maher ; Andersen, Mathias Bækbo; Nishimoto, Mamoru; Clausen, Mads Hartvig; Urashima, Tadasu; Svensson, Birte; Kitaoka, Motomitsu.

    In: Glycobiology, Vol. 24, No. 2, 2014, p. 20208-216.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  16. Published

    DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families. / Sander, Adam F.; Lavstsen, Thomas; Rask, Thomas Salhøj; Lisby, Michael; Salanti, Ali; Fordyce, Sarah L.; Jespersen, Jakob S.; Carter, Richard; Deitsch, Kirk W.; Theander, Thor G.; Pedersen, Anders Gorm; Arnot, David E.

    In: Nucleic Acids Research, Vol. 42, No. 4, 2014, p. 202270-2281.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  17. Published

    Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population. / Eriksson, Robert; Werge, Thomas; Jensen, Lars Juhl; Brunak, Søren.

    In: Drug Safety, Vol. 37, No. 4, 2014, p. 237-247.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  18. Published

    Effect of subinhibitory concentrations of four commonly used biocides on the conjugative transfer of Tn916 in Bacillus subtilis. / Seier-Petersen, Maria Amalie; Jasni, A.; Aarestrup, Frank Møller; Vigre, Håkan; Mullany, P.; Roberts, A. P.; Agersø, Yvonne.

    In: Journal of Antimicrobial Chemotherapy, Vol. 69, No. 2, 2014, p. 343-348.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  19. Published
  20. Published
  21. Published
  22. Published

    Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment. / Carrasco Pro, S.; Zimic, M.; Nielsen, Morten.

    In: Tissue Antigens, Vol. 83, No. 2, 2014, p. 94-100.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  23. Published

    Large-scale bioreactor production of the herbicide-degrading Aminobacter sp. strain MSH1. / Schultz-Jensen, Nadja; Knudsen, Berith Elkær; Frkova, Zuzana; Aamand, Jens; Johansen, Tina; Thykær, Jette; Sørensen, Sebastian R.

    In: Applied Microbiology and Biotechnology, Vol. 98, No. 5, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  24. Published

    Linear versus conformational epitopes of three cow's milk allergens. / Bøgh, Katrine Lindholm; Madsen, Jeanette Lund; Kroghsbo, Stine; Madsen, Charlotte Bernhard; Barkholt, Vibeke.

    In: Clinical and Translational Allergy, Vol. 4 , No. Suppl 2, P23, 2014.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  25. Published

    Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis. / Jiricny, Natalie; Molin, Søren; Foster, Kevin; Diggle, Stephen P.; Scanlan, Pauline D.; Ghoul, Melanie; Johansen, Helle Krogh; Santorelli, Lorenzo A.; Popat, Roman; West, Stuart A.; Griffin, Ashleigh S.

    In: P L o S One, Vol. 9, No. 1, 2014, p. Article No.: e83124.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  26. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection.. / Christensen, Dan Ploug; Gysemans, Conny; Lundh, Morten; Dahllöf, Mattias Salling; Noesgaard, Daniel; Schmidt, Søren Fisker; Mandrup, Susanne; Birkbak, Nicolai Juul; Workman, Christopher; Piemonti, Lorenzo; Blaabjerg, Lykke; Monzani, Valmen; Fossati, Gianluca; Mascagni, Paolo; Paraskevas, Steven; Aikin, Reid A; Billestrup, Nils; Grunnet, Lars Groth; Dinarello, Charles A; Mathieu, Chantal; Mandrup-Poulsen, Thomas.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 3, 2014, p. 1055-1059.

    Publication: ResearchJournal article – Annual report year: 2014

  27. Published

    Micropeptins from Microcystis sp. collected in Kabul Reservoir, Israel. / Bladt, Tanja Thorskov; Kalifa-Aviv, Sivan; Larsen, Thomas Ostenfeld; Carmeli, Shmuel.

    In: Tetrahedron, Vol. 70, No. 4, 2014, p. 936-943.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  28. Published

    Multiparametric Bioinformatics Distinguish the CD4/CD8 Ratio as a Suitable Laboratory Predictor of Combined T Cell Pathogenesis in HIV Infection. / Buggert, Marcus; Frederiksen, Juliet Wairimu; Noyan, Kajsa; Svärd, Jenny; Barqasho, Babilonia; Sönnerborg, Anders; Lund, Ole; Nowak, Piotr; Karlsson, Annika C.

    In: Journal of Immunology, Vol. 192, No. 5, 2014, p. 2099-2108.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  29. Published

    Natural mannosylation of HIV-1 gp120 imposes no immunoregulatory effects in primary human plasmacytoid dendritic cells. / Søndergaard, Jonas Nørskov; Vinner, Lasse; Pedersen, Susanne Brix.

    In: Molecular Immunology, Vol. 59, No. 2, 2014, p. 180-187.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  30. Published

    Polyamines are essential for virulence in Salmonella enterica serovar Gallinarum despite evolutionary decay of polyamine biosynthesis genes. / Schroll, Casper; Christensen, Jens P.; Christensen, Henrik; Pors, Susanne E.; Thorndahl, Lotte; Jensen, Peter Ruhdal; Olsen, John E.; Jelsbak, Lotte.

    In: Veterinary Microbiology, Vol. 170, No. 1-2, 2014, p. 144-150.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  31. Published

    Pre‐natal undernutrition and post‐natal overnutrition are associated with permanent changes in hepatic metabolism markers and fatty acid composition in sheep. / Hou, L.; Hellgren, Lars; Kongsted, A. H.; Vaag, A.; Nielsen, M. O.

    In: Acta Physiologica (Print), Vol. 210, No. 2, 2014, p. 317-329.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  32. Published

    Proteome reference maps of the Lotus japonicus nodule and root. / Dam, Svend Secher; Dyrlund, Thomas F.; Ussatjuk, Anna; Jochimsen, Bjarne; Nielsen, Kasper; Goffard, Nicolas; Ventosa, Miguel; Lorentzen, Andrea; Gupta, Vikas; Andersen, Stig U. ; Enghild, Jan J.; Ronson, Clive W.; Roepstorff, Peter; Stougaard, Jens.

    In: Journal of Proteomics, Vol. 14, 2014, p. 230-240.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  33. Published
  34. Published

    Robust Estimation of Diffusion-Optimized Ensembles for Enhanced Sampling. / Tian, Pengfei; Jónsson, Sigurdur Æ.; Ferkinghoff-Borg, Jesper; Krivov, Sergei V.; Lindorff-Larsen, Kresten; Irbäck, Anders; Boomsma, Wouter.

    In: Journal of Chemical Theory and Computation, Vol. 10, No. 2, 2014, p. 543-553.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  35. Published

    Secreted single‐stranded DNA is involved in the initial phase of biofilm formation by Neisseria gonorrhoeae. / Zweig, Maria; Schork, Sabine; Koerdt, Andrea; Siewering, Katja; Sternberg, Claus; Thormann, Kai; Albers, Sonja‐Verena; Molin, Søren; Does, Chris, van der.

    In: Environmental Microbiology, Vol. 16, No. 4, 2014, p. 1040-1052.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  36. Published

    Sequence and comparative analysis of Leuconostoc dairy bacteriophages. / Kot, Witold; Hansen, Lars Henrik; Neve, Horst; Hammer, Karin; Jacobsen, Susanne; Pedersen, Per D.; Sørensen, Søren J.; Heller, Knut J.; Vogensen, Finn K.

    In: International Journal of Food Microbiology, Vol. 176, 2014, p. 29-37.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  37. Published

    Size of quorum sensing communities. / Ferkinghoff-Borg, Jesper; Sams, Thomas.

    In: Molecular BioSystems, Vol. 10, No. 103, 2014, p. 103-109.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  38. Published

    Solid‐Phase Synthesis and Biological Evaluation of N‐Dipeptido L‐Homoserine Lactones as Quorum Sensing Activators. / Hansen, Mette Reimert; Le Quement, Sebastian Thordal; Jakobsen, Tim Holm; Skovstrup, Søren; Taboureau, Olivier ; Tolker‐Nielsen, Tim; Givskov, Michael Christian; Nielsen, Thomas Eiland.

    In: ChemBioChem, Vol. 15, No. 3, 2014, p. 460-465.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  39. Published

    Solonamide B Inhibits Quorum Sensing and Reduces Staphylococcus aureus Mediated Killing of Human Neutrophils. / Nielsen, Anita; Månsson, Maria; Bojer, Martin S.; Gram, Lone; Larsen, Thomas Ostenfeld; Novick, Richard P.; Frees, Dorte; Frøkiær, Hanne; Ingmer, Hanne.

    In: P L o S One, Vol. 9, No. 1, e84992, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  40. Published

    Stability of the intra- and extracellular toxins of Prymnesium parvum using a microalgal bioassay. / Blossom, Hannah Eva; Andersen, Nikolaj Gedsted; Rasmussen, Silas Anselm; Hansen, Per Juel.

    In: Harmful Algae, Vol. 32, 2014, p. 11-21.

    Publication: ResearchJournal article – Annual report year: 2014

  41. Published

    Studies on genetic diversity of bovine viral diarrhea viruses in Danish cattle herds. / Nagy, Abdou; Fahnøe, Ulrik; Rasmussen, Thomas Bruun; Uttenthal, Åse.

    In: Virus Genes, Vol. 48, No. 2, 2014, p. 376-380.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  42. Published
  43. Published

    The effect of a short-term high-fat overfeeding on plasma levels of amino acids in young, healthy men with low or normal birth weight. / Ribel-Madsen, Amalie; Hellgren, Lars; Brøns , Charlotte; Ribel-Madsen , Rasmus; B. Newgard , Christopher; A. Vaag , Allan.

    2014. Abstract from The Power of Programming Conference, Munich, Germany.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2014

  44. Published

    The effect of a short-term high-fat overfeeding on plasma levels of amino acids in young, healthy men with low or normal birth weight. / Ribel-Madsen, Amalie; Hellgren, Lars; Brøns , Charlotte; Ribel-Madsen , Rasmus; B. Newgard , Christopher; A. Vaag , Allan.

    2014. Abstract from The 11th Biennial ISSFAL Congress 2014, Stockholm, Sweden.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2014

  45. Published

    The genome of a Late Pleistocene human from a Clovis burial site in western Montana.. / Rasmussen, Morten; Anzick, Sarah L.; Waters, Michael R; Skoglund, Pontus; DeGiorgio, Michael; Stafford, Thomas W, Jr; Rasmussen, Simon; Moltke, Ida; Albrechtsen, Anders; Doyle, Shane M; Poznik, G David; Gudmundsdottir, Valborg; Yadav, Rachita; Malaspinas, Anna Sapfo; White, Samuel Stockton, 5th; Allentoft, Morten Erik; Cornejo, Omar E.; Tambets, Kristiina; Eriksson, Anders; Heintzman, Peter D.; Karmin, Monika; Korneliussen, Thorfinn Sand; Meltzer, David J.; Pierre, Tracey Lynn; Stenderup, Jesper; Saag, Lauri; Warmuth, Vera M; Lopes, Margarida C; Malhi, Ripan S.; Brunak, Søren; Sicheritz-Pontén, Thomas; Barnes, Ian; Collins, Matthew; Orlando, Ludovic Antoine Alexandre; Balloux, Francois; Manica, Andrea; Gupta, Ramneek; Metspalu, Mait; Bustamante, Carlos D; Jakobsson, Mattias; Nielsen, Rasmus; Willerslev, Eske.

    In: Nature, Vol. 506, No. 7487, 2014, p. 225-229.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  46. Published

    The Role of the st313-td Gene in Virulence of Salmonella Typhimurium ST313. / Herrero-Fresno, Ana; Wallrodt, Inke; Leekitcharoenphon, Pimlapas; Olsen, John Elmerdahl; Aarestrup, Frank Møller; Hendriksen, Rene S.

    In: PLOS ONE, Vol. 9, No. 1, e84566, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  47. Published

    Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution. / Dewhurst, Sally M.; McGranahan, Nicholas; Burrell, Rebecca A.; Rowan, Andrew J.; Grönroos, Eva; Endesfelder, David; Joshi, Tejal; Mouradov, Dmitri; Gibbs, Peter; Ward, Robyn L.; Hawkins, Nicholas J.; Szallasi, Zoltan Imre; Sieber, Oliver M.; Swanton, Charles.

    In: Cancer Discovery, Vol. 4, No. 2, 2014, p. 175-185.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  48. Published
  49. Published

    α-Amylase: an enzyme specificity found in various families of glycoside hydrolases. / Janeček, Štefan; Svensson, Birte; MacGregor, E. Ann.

    In: Cellular and Molecular Life Sciences, Vol. 71, No. 7, 2014, p. 1149-1170.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  50. 2013
  51. Published

    31P gain of chromosomal region 15q26 cause increased expression of blm and fanci, and is associated with sensitivity to platinum chemotherapy in triple negative breast cancer. / Birkbak, Nicolai Juul; Li, Y.; Bowman-Collin, C.; Iglehart, J.D.; Silver, D.; Wang, Z.C.; Szallasi, Zoltan Imre; Richardson, A.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii22.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  52. Published
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