Network Reconstructions and in silico Biology

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Organisation profile

Network Reconstruction and in-silico Biology The section reconstruct metabolic, protein synthesis, and regulatory networks for industrially-relevant microorganismsand products using bioinformatic approaches and manual curation. We develop constraint-based modeling approaches, reconstruction methods, and omics data integration approaches to understand biological phenotypes.The majority of activities in the section takes place at the Center satellite at UCSD.

We use adaptive laboratory evolution to study dynamics of bacterial adaptation, genetic causality, and microbial bioprocessing capabilities. We distribute the reconstructed networks and developed methods to the core team to drive metabolic engineering through modeling.

The section is headed by Professor Bernhard Palsson.

 

Contact information

Fremtidsvej 3
DK-2970
Hørsholm
Denmark
  • Phone: +45 4525 8000
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  • Nature Biotechnology

    ISSNs: 1087-0156, 10870156

    Nature Publishing Group, United States

    FI (2013): 2, ISI indexed (2013): yes

    Central database

    Journal

  • Molecular Systems Biology

    ISSNs: 1744-4292

    Nature Publishing Group, United Kingdom

    FI (2013): 2, ISI indexed (2013): yes

    Central database

    Journal

  • P L o S Genetics

    ISSNs: 1553-7390, 15537390

    Public Library of Science, United States

    FI (2013): 2, ISI indexed (2013): yes

    Central database

    Journal

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ID: 4447