Organisation profile
CBM focuses on control of pathogenic bacteria, in particular opportunistic pathogenic bacteria which cause chronic infections. These bacteria live as biofilm communities and they have become evident in environmental, industrial, and medical problems. NIH estimates biofilms are involved in 60% of all bacterial infections. Biofilms can withstand the action of the immune system and tolerate the highest deliverable doses of antibiotics. At the present, biofilm infections cannot be efficiently treated.
Biofilm infections are becoming more and more common with the increase in aging population and the concomitant use of artificial organs and joints which create ideal environments for a biofilm based infection.
CBM therefore addresses a very important problem in society which at the moment no other Danish institution deals with.
The aim is to devise new anti-bacterial strategies and develop “intelligent” treatment scenarios for medical and industrial purposes and educate civil engineers and PhD’s with expertise in the field of biomedical engineering.
Understand biofilm biology
Develop anti-biofilm drugs with high target specificity
No development of resistance
No effect on beneficial flora
Natural prophylaxis and treatment against chronic infections.
Contact information
Matematiktorvet, 301
DK-2800, Kgs. Lyngby
Denmark
- Phone: +45 4525 2500
Publications
(158)- Published
Bacterial Adhesion & Blocking Bacterial Adhesion
Publication: Research › Ph.d. thesis – Annual report year: 2008
- Published
The ferric yersiniabactin uptake receptor FyuA is required for efficient biofilm formation by urinary tract infectious Escherichia coli in human urine
Publication: Research - peer-review › Journal article – Annual report year: 2008
- Published
Quorum sensing antagonism from marine organisms
Publication: Research - peer-review › Journal article – Annual report year: 2008
Most frequent journals
Journal of Bacteriology
ISSNs: 0021-9193
American Society for Microbiology, United States
FI (2012): 1, ISI indexed (2012): yes
Central database
Journal
Applied and Environmental Microbiology
ISSNs: 0099-2240, 00992240
American Society for Microbiology, United States
FI (2012): 2, ISI indexed (2012): yes
Central database
Journal
Molecular Microbiology
ISSNs: 0950-382X
Wiley-Blackwell Publishing Ltd., United Kingdom
FI (2012): 1, ISI indexed (2012): yes
Central database
Journal
Projects
(11)- Completed
- Completed
Most frequent publishers
Most downloaded publications
- 162
Differentiation in Pseudomonas Aeruginosa Biofilms
Publication: Research › Ph.d. thesis – Annual report year: 2007
downloads
Latest activities and conferences
ID: 2913