Center for Biological Sequence Analysis

  1. 2015
  2. E-pub ahead of print

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways.. / Ninel Hansen, Stine; Westergaard, David ; Borg Houlberg Thomsen, Mathilde; Vistesen, Mette; Nguyen Do, Khoa; Fogh, Louise; Belling, Kirstine C.; Wang, Jun; Yang, Huanming; Gupta, Ramneek; Ditzel, Henrik Jørn; Moreira, José ; Brünner, Nils; Stenvang, Jan; Schrohl, Anne-Sofie.

    In: Tumor Biology, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  3. Accepted/In press

    Acylcarnitine plasma levels suggest incomplete mitochondrial fatty acid oxidation in young, healthy men with low birth weight. / Ribel-Madsen, Amalie; Ribel-Madsen, Rasmus; Brøns, Charlotte; B. Newgard, Christopher; Vaag, Allan; Hellgren, Lars.

    2015. Abstract from 28th Nordic Lipid Symposium, Reykjavik, Iceland.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  4. Published

    Airway Mucosal Immune-suppression in Neonates of Mothers Receiving A(H1N1)pnd09 Vaccination During Pregnancy. / Pedersen, Susanne Brix; Bischoff, Anne L.; Folsgaard, Nilofar V.; Vissing, Nadja H.; Birch, Sune; Bisgaard, Hans .

    In: Pediatric Infectious Disease Journal, Vol. 34, No. 1, 2015, p. 84-90.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  5. Published

    AllelicImbalance: An R/ bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencing. / Gådin, Jesper R.; van't Hooft, Ferdinand M.; Eriksson, Per; Folkersen, Lasse.

    In: BMC Bioinformatics, Vol. 16, No. 1, 2015, p. 194.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  6. E-pub ahead of print

    A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death. / Rondas, Dieter; Gudmundsdottir, Valborg; D’Hertog, Wannes; Crèvecoeur, Inne; Waelkens, Etienne; Brunak, Søren; Mathieu, Chantal; Overbergh, Lut.

    In: Proteomics - Clinical Applications, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  7. Published

    Archival Bone Marrow Samples: Suitable for Multiple Biomarker Analysis?. / Lund, Bendik; Najmi, A. Laeya; Wesolowska, Agata; Landsem, Veslemoy M.; Rasmussen, Kirsten K.; Borst, Louise; Gupta, Ramneek; Schmiegelow, Kjeld; Klungland, Helge.

    In: Applied Immunohistochemistry & Molecular Morphology, Vol. 23, No. 1, 2015, p. 71-77.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. Published
  9. Published

    Automated benchmarking of peptide-MHC class I binding predictions. / Trolle, Thomas; Metushi, Imir G.; Greenbaum, Jason; Kim, Yohan; Sidney, John; Lund, Ole; Sette, Alessandro; Peters, Bjoern; Nielsen, Morten.

    In: Bioinformatics, Vol. 31, No. 13, 2015, p. 2174-2181.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  10. Published

    Bioinformatics prediction of swine MHC class I epitopes from Porcine Reproductive and Respiratory Syndrome Virus. / Welner, Simon; Nielsen, Morten; Lund, Ole; Jungersen, Gregers; Larsen, Lars Erik.

    2015. Abstract from Keystone Symposia on Molecular and Cellular Biology: Accelerating life science discovery, Keystone, United States.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  11. Published
  12. Published

    Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. / McGranahan, Nicholas; Favero, Francesco; de Bruin, Elza C.; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Science Translational Medicine, Vol. 7, No. 283, 283ra54, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  13. Published

    Defining the microbial effluxome in the content of the host-microbiome interaction. / Ioannidis, Anastasios; Magana, Maria; Bologa, Cristian G.; Oprea, Tudor I.; Paulsen, Ian T.; Tegos, George P.

    In: Frontiers in Pharmacology, Vol. 6, 31, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  14. Published

    Developing a Molecular Roadmap of Drug-Food Interactions. / Jensen, Kasper; Ni, Yueqiong; Panagiotou, Gianni; Kouskoumvekaki, Irene.

    In: P L o S Computational Biology (Online), Vol. 11, No. 2, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  15. Published

    Distinct summer and winter bacterial communities in the active layer of Svalbard permafrost revealed by DNA- and RNA-based analyses. / Schostag, Morten; Stibal, Marek; Jacobsen, Carsten S.; Bælum, Jacob; Tas, Neslihan; Elberling, Bo; Jansson, Janet K.; Semenchuk, Philipp; Prieme, Anders.

    In: Frontiers in Microbiology, Vol. 6, 399, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  16. Published

    Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance. / Jensen, Niels F.; Stenvang, Jan; Beck, Mette Kristina; Hanáková, Barbora; Belling, Kirstine C.; Nguyen Do, Khoa; Viuff, Birgitte; Nygård, Sune B.; Gupta, Ramneek; Rasmussen, Mads H.; Tarpgaard, Line S.; Hansen, Tine P.; Budinská, Eva; Pfeiffer, Per; Bosman, Fred; Tejpar, Sabine; Roth, Arnaud; Delorenzi, Mauro; Andersen, Claus L.; Rømer, Maria U.; Brünner, Nils; Moreira, José M.A.

    In: Molecular Oncology, Vol. 9, No. 6, 2015, p. 1169-1185.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  17. Published

    Evidence of interactions between aroma compounds and the CB1 receptor opens new routes for regulation of food intake. / Le Bon, Anne-Marie; Audouze, Karine Marie Laure; Taboureau, Olivier ; Burton, Kathryn; Belloir, Christine; Desmetz, Catherine; Brunak, Søren; Guichard, Elisabeth; Tromelin, Anne.

    In: Chemical Senses, Vol. 40, No. 3, 2015, p. 280-280.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2015

  18. E-pub ahead of print
  19. Accepted/In press

    FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses. / Simon, Christian; Kudahl, Ulrich Johan; Sun, Jing; Olsen, Lars Rønn; Zhang, Guang Lan; Reinherz, Ellis L.; Brusic, Vladimir.

    In: Journal of Immunology Research, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  20. Published

    Gene expression analysis identifies global gene dosage sensitivity in cancer. / Fehrmann, Rudolf S. N.; Karjalainen, Juha M.; Krajewska, Malgorzata; Westra, Harm-Jan; Maloney, David; Simeonov, Anton; Pers, Tune Hannes; Hirschhorn, Joel N.; Jansen, Ritsert C.; Schultes, Erik A.; van Haagenl, Herman H. H. B. M.; de Vries, Elisabeth G. E.; Meerman, Gerard J. te; Wijmenga, Cisca; van Vugt, Marcel A. T. M.; Franke, Lude.

    In: Nature Genetics, Vol. 47, No. 2, 2015, p. 115-125.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  21. Published

    Genomic Dissection of Travel-Associated Extended-Spectrum-Beta-Lactamase-Producing Salmonella enterica Serovar Typhi Isolates Originating from the Philippines: a One-Off Occurrence or a Threat to Effective Treatment of Typhoid Fever?. / Hendriksen, Rene S.; Leekitcharoenphon, Pimlapas; Mikoleit, Matthew; Jensen, Jacob Dyring; Kaas, Rolf Sommer; Roer, Louise; Joshi, Heena B.; Pornruangmong, Srirat; Pulsrikarn, Chaiwat; Gonzalez-Aviles, Gladys D.; Reuland, E. Ascelijn; Al Naiemi, Nashwan; Wester, Astrid Louise; Aarestrup, Frank Møller; Hasman, Henrik.

    In: Journal of Clinical Microbiology, Vol. 53, No. 2, 2015, p. 677-680.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  22. Published

    Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients. / Wesolowska, Agata; Borst, L.; Dalgaard, Marlene Danner; Yadav, Rachita; Rasmussen, K. K. ; Wehner, Peder Skov; Rasmussen, M.; Ørntoft, T.F.; Nordentoft, I.; Koehler, R.; Sicheritz-Pontén, Thomas; Gautier, Laurent; Brunak, Søren; Gupta, Ramneek.

    In: Leukemia, Vol. 29, 2015, p. 297-303.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  23. Published

    Genomic Signature of Multidrug-Resistant Salmonella enterica Serovar Typhi Isolates Related to a Massive Outbreak in Zambia between 2010 and 2012.. / Hendriksen, Rene S.; Leekitcharoenphon, Pimlapas; Lukjancenko, Oksana; Lukwesa-Musyani, Chileshe; Tambatamba, Bushimbwa; Mwaba, John; Kalonda, Annie; Nakazwe, Ruth; Kwenda, Geoffrey; Jensen, Jacob Dyring; Svendsen, Christina Aaby; Dittmann, Karen K.; Kaas, Rolf Sommer; Cavaco, Lina; Aarestrup, Frank Møller; Hasman, Henrik; Mwansa, James C. L.

    In: Journal of Clinical Microbiology, Vol. 53, No. 1, 2015, p. 262-272.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  24. Published

    Gliadin affects glucose homeostasis and intestinal metagenome in C57BL6 mice fed a high-fat diet. / Zhang, Li; Hansen, Axel Kornerup; Bahl, Martin Iain; Hansen, Camilla Hartmann Friis; Andersen, Daniel; Pedersen, Susanne Brix; Hellgren, Lars; Licht, Tine Rask.

    2015. Abstract from Keystone Symposia - Gut Microbiota Modulation of Host Physiology: The Search for Mechanism, Keystone, Colorado, United States.

    Publication: Research - peer-reviewConference abstract for conference – Annual report year: 2015

  25. Published

    Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome. / Favero, Francesco; McGranahan, N.; Salm, M.; Birkbak, Nicolai Juul; Sanborn, J. Z.; Benz, S. C.; Becq, J.; Peden, J. F.; Kingsbury, Z.; Grocok, R. J.; Eklund, Aron Charles; Szallasi, Zoltan Imre.

    In: Annals of Oncology, Vol. 26, No. 5, 2015, p. 880-887.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  26. Published

    Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macroevolution of a double minute chromosome.. / Favero, Francesco; McGranahan, Nicholas; Salm, Maximilian P.; Birkbak, Nicolai Juul; Sanborn, J. Zachary ; Benz, Stephen C. ; Becq, Jennifer; Peden, John F. ; Kingsbury, Zoya ; Grocok, Russell J. ; Eklund, Aron Charles.

    In: Annals of Oncology, Vol. 26, No. 5, 2015, p. 880-887.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  27. Published

    Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling. / Basse, Astrid L.; Dixen, Karen; Yadav, Rachita; Tygesen, Malin P.; Qvortrup, Klaus; Kristiansen, Karsten; Quistorff, Bjorn; Gupta, Ramneek; Wang, Jun; Hansen, Jacob B.

    In: B M C Genomics, Vol. 16, No. 215, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  28. Published

    Hand eczema and stratum corneum ceramides. / Jungersted, J. M.; Høgh, Julie Kaae; Hellgren, Lars; Wilkinson, S.; Jemec, G. B. E.; Agner, T.

    In: Clinical and Experimental Dermatology, Vol. 40, No. 3, 2015, p. 243-246.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  29. Published

    Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection. / Esaki, Hitokazu; Ewald, David Adrian; Ungar, Benjamin; Rozenblit, Mariya; Zheng, Xiuzhong; Xu, Hui; Estrada, Yeriel D.; Peng, Xiangyu; Mitsui, Hiroshi; Litman, Thomas; Suarez-Farinas, Mayte; Krueger, James G.; Guttman-Yassky, Emma.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 1, 2015, p. 153-163.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  30. Published

    Identification of possible adverse drug reactions in clinical notes : The case of glucose-lowering medicines. / Warrer, Pernille; Jensen, Peter Bjødstrup; Aagaard, Lise; Jensen, Lars Juhl; Brunak, Søren; Krag, Malene Hammer; Rossing, Peter; Almdal, Thomas; Andersen, Henrik Ullits; Hansen, Ebba Holme.

    In: Journal of Research in Pharmacy Practice, Vol. 4, No. 2, 2015, p. 64-72.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  31. Published

    Individualization of treatments with drugs metabolized by CES1 : combining genetics and metabolomics. / Rasmussen, Henrik B.; Bjerre, Ditte; Linnet, Kristian; Juergens, Gesche; Dalhoff, Kim; Stefansson, Hreinn; Hankemeier, Thomas; Kaddurah-Daouk, Rima; Taboureau, Olivier ; Brunak, Søren; Houmann, Tine; Jeppesen, Pia; Pagsberg, Anne Katrine; Plessen, Kerstin; Dyrborg, Jorgen; Hansen, Peter R.; Hansen, Poul Erik; Hughes, Tim; Werge, Thomas.

    In: Pharmacogenomics, Vol. 16, No. 6, 2015, p. 649-665.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  32. Published

    Insights from 20 years of bacterial genome sequencing. / Land, Miriam; Hauser, Loren; Jun, Se-Ran; Nookaew, Intawat; Leuze, Michael R.; Ahn, Tae-Hyuk; Karpinets, Tatiana; Lund, Ole; Kora, Guruprased; Wassenaar, Trudy; Poudel, Suresh; Ussery, David.

    In: Functional & Integrative Genomics, Vol. 15, No. 2, 2015, p. 141-161.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  33. Published

    Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. / So, Jonathan; Pasculescu, Adrian; Dai, Anna Y.; Williton, Kelly; James, Andrew; Nguyen, Vivian; Creixell, Pau; Schoof, Erwin M.; Sinclair, John; Barrios-Rodiles, Miriam; Gu, Jun; Krizus, Aldis; Williams, Ryan; Olhovsky, Marina; Dennis, James W.; Wrana, Jeffrey L.; Linding, Rune; Jørgensen, Claus; Pawson, Tony; Colwill, Karen.

    In: Science Signaling, Vol. 8, No. 371, rs3, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  34. Published

    Lactococcus lactis Thioredoxin Reductase Is Sensitive to Light Inactivation. / Björnberg, Olof; Viennet, Thibault; Skjoldager, Nicklas; Curovic, Aida; Nielsen, Kristian Fog; Svensson, Birte; Hagglund, P.

    In: Biochemistry, Vol. 54, No. 8, 2015, p. 1628-1637.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  35. E-pub ahead of print
  36. Published

    LYRA, a webserver for lymphocyte receptor structural modeling.. / Schantz Klausen, Michael; Anderson, Mads Valdemar; Jespersen, Martin Closter; Nielsen, Morten; Marcatili, Paolo.

    In: Nucleic Acids Research, Vol. 43, No. W1, 2015, p. W349-W355.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  37. Published
  38. Published

    Metagenomic heterogeneity explains dual immune effects of endotoxins. / Pedersen, Susanne Brix; Eriksen, Carsten; Larsen, Jeppe Madura; Bisgaard, Hans Flinker.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 1, 2015, p. 277-280.

    Publication: Research - peer-reviewComment/debate – Annual report year: 2015

  39. Published

    Microbial Biofilm as a Smart Material. / Garde, Christian; Welch, Martin; Ferkinghoff-Borg, Jesper; Sams, Thomas.

    In: Sensors, Vol. 15, No. 2, 2015, p. 4229-4241.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  40. Published

    miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator. / Husby, Simon; Ralfkiær, Ulrik Methner; Garde, Christian; Zandi, Roza; Ek, Sara; Kolstad, Arne; Jerkeman, Mats; Laurell, Anna; Räty, Riikka; Pedersen, Lone B.; Pedersen, Anja; Ehinger, Mats; Sundström, Christer; Karjalainen-Lindsberg, Marja-Liisa; Delabie, Jan; Clasen-Linde, Erik; Brown, Peter; Cowland, Jack B.; Workman, Christopher; Geisler, Christian H.; Grønbæk, Kirsten.

    In: Blood, Vol. 125, No. 17, 2015, p. 2669-2677.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  41. Published

    Molecular Analysis of Asymptomatic Bacteriuria Escherichia coli Strain VR50 Reveals Adaptation to the Urinary Tract by Gene Acquisition. / Beatson, Scott A.; Ben Zakour, Nouri L.; Totsika, Makrina; Forde, Brian M.; Watts, Rebecca E.; Mabbett, Amanda N.; Szubert, Jan M.; Sarkar, Sohinee; Phan, Minh-Duy; Peters, Kate M.; Petty, Nicola K.; Alikhan, Nabil-Fareed; Sullivan, Mitchell J.; Gawthorne, Jayde A.; Stanton-Cook, Mitchell; Nhu, Nguyen Thi Khanh; Chong, Teik Min; Yin, Wai-Fong; Chan, Kok-Gan; Hancock, Viktoria ; Ussery, David W.; Ulett, Glen C.; Schembri, Mark A.

    In: Infection and Immunity, Vol. 83, No. 5, 2015, p. 1749-1764.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  42. Published

    Multilocus Heterozygosity and Coronary Heart Disease: Nested Case-Control Studies in Men and Women. / Mukamal, Kenneth J.; Jensen, Majken K.; Pers, Tune Hannes; Pai, Jennifer K.; Kraft, Peter; Rimm, Eric B.

    In: PLOS ONE, Vol. 10, No. 5, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  43. Accepted/In press
  44. Published

    Multi-omic profiling of EPO-producing CHO cell panel reveals metabolic adaptation to heterologous protein production. / Ley, Daniel; Kazemi Seresht, Ali; Engmark, Mikael; Magdenoska, Olivera; Nielsen, Kristian Fog; Kildegaard, Helene Faustrup; Andersen, Mikael Rørdam.

    2015. Poster session presented at 24th ESACT meeting, Barcelona, Spain.

    Publication: Research - peer-reviewPoster – Annual report year: 2015

  45. Published

    Neonates with reduced neonatal lung function have systemic low-grade inflammation. / Chawes, Bo L.K.; Stokholm, Jakob; Bønnelykke, Klaus; Pedersen, Susanne Brix; Bisgaard, Hans Flinker.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 6, 2015, p. 1450-1456.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  46. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. / Besenbacher, Søren; Liu, Siyang; Gonzalez-Izarzugaza, Jose Maria; Grove, Jakob; Belling, Kirstine C.; Bork-Jensen, Jette; Huang, Shujia; Dam-Als, Thomas; Li, Shengting; Yadav, Rachita; Yadav, Rachita; Rubio García, Arcadio; Lescai, Francesco; Demontis, Ditte ; Rao, Junhua ; Ye, Weijian ; Mailund, Thomas; Friborg, Rune M. ; Pedersen, Christian N. S.; Xu, Ruiqi; Sun, Jihua; Liu, Hao ; Wang, Ou ; Cheng, Xiaofang ; Flores Santa Cruz, David; Rydza, Emil Karol; Rapacki, Kristoffer; Sørensen, John Damm; Chmura, Piotr Jaroslaw; Westergaard, David; Dworzynski, Piotr; Sørensen, Thorkild I. A.; Lund, Ole; Hansen, Torben; Xu, Xun; Li, Ning; Bolund, Lars; Pedersen, Oluf; Eiberg, Hans; Krogh, Anders; Børglum, Anders D.; Brunak, Søren; Kristiansen, Karsten; Schierup, Mikkel H; Jun, Wang; Gupta, Ramneek; Villesen, Palle ; Rasmussen, Simon.

    In: Nature Communications, Vol. 6, 5969, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  47. Published

    Pan-Genome Analysis of Human Gastric Pathogen H. pylori: Comparative Genomics and Pathogenomics Approaches to Identify Regions Associated with Pathogenicity and Prediction of Potential Core Therapeutic Targets. / Ali, Amjad; Naz, Anam; Soares, Siomar C.; Bakhtiar, Marriam; Tiwari, Sandeep; Hassan, Syed S.; Hanan, Fazal; Ramos, Rommel; Pereira, Ulisses; Barh, Debmalya; Pereira Figueiredo, Henrique Cesar; Ussery, David; Miyoshi, Anderson; Silva, Artur; Azevedo, Vasco.

    In: Journal of Biomedicine and Biotechnology, Vol. 2015, 139580, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  48. Published
  49. Published

    Reduced ex vivo stimulated IL-6 response in infants randomized to fish oil from 9 to 18 months, especially among PPARG2 and COX2 wild types. / Harslof, Laurine B. S.; Damsgaard, Camilla T.; Andersen, Anders D.; Aakjaer, Ditte L.; Michaelsen, Kim F.; Hellgren, Lars I.; Frøkiær, Hanne; Vogel, Ulla; Lauritzen, Lotte.

    In: Prostaglandins, Leukotrienes & Essential Fatty Acids, Vol. 94, 2015, p. 21-27.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  50. Published

    Relationship of postoperative thrombocytosis and survival of patients with colorectal cancer. / Josa, Valeria; Krzystanek, Marcin; Eklund, Aron Charles; Salamon, Ferenc; Zarand, Attila; Szallasi, Zoltan Imre; Baranyai, Zsolt.

    In: International Journal of Surgery, Vol. 18, 2015, p. 1-6.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  51. Published

    Renal impairment and late toxicity in germ-cell cancer survivors.. / Lauritsen, J.; Mortensen, M. S.; Kier, M. G. G.; Christensen, I. J.; Agerbaek, M.; Gupta, Ramneek; Daugaard, G.

    In: Annals of Oncology, Vol. 26, No. 1, 2015, p. 173-178.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  52. Published

    RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications. / Suárez-Fariñas, Mayte; Ungar, Benjamin; Correa da Rosa, Joel; Ewald, David Adrian; Rozenblit, Mariya; Gonzalez, Juana; Xu, Hui; Zheng, Xiuzhong; Peng, Xiangyu; Estrada, Yeriel D.; Dillon, Stacey ; Krueger, James G.; Guttman-Yassky, Emma.

    In: Journal of Allergy and Clinical Immunology, Vol. 135, No. 5, 2015, p. 1218-1227.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  53. Published
  54. Published

    Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling. / Kristensen, Jacob Hull; Karsdal, Morten A.; Sand, Jannie M. B.; Willumsen, Nicholas; Diefenbach, Claudia; Svensson, Birte; Hägglund, Per; Oersnes-Leeming, Diana J.

    In: BMC Pulmonary Medicine, Vol. 15, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  55. Published

    SNPsnap: a Web-based tool for identification and annotation of matched SNPs. / Pers, Tune Hannes; Timshel, Pascal; Hirschhorn, Joel N.

    In: Bioinformatics, Vol. 31, No. 3, 2015, p. 418-420.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  56. Published

    Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer. / Su, Ying; Subedee, Ashim; Bloushtain-Qimron, Noga; Savova, Virginia; Krzystanek, Marcin; Li, Lewyn; Marusyk, Andriy; Tabassum, Doris P.; Zak, Alexander; Szallasi, Zoltan Imre.

    In: Cell Reports, Vol. 11, No. 10, 2015, p. 1549-1563.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  57. Published

    Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria. / Lau, Clinton K.Y.; Turner, Louise; Jespersen, Jakob S.; Lowe, Edward D. ; Petersen, Bent; Wang, Christian W.; Petersen, Jens E.V.; Lusingu, John; Theander, Thor G.; Lavstsen, Thomas; Higgins, Matthew K.

    In: Cell Host & Microbe, Vol. 17, 2015, p. 118-129.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  58. Published

    Tabhu: tools for antibody humanization.. / Olimpieri, Pier Paolo; Marcatili, Paolo; Tramontano, Anna.

    In: Bioinformatics, Vol. 31, No. 3, 2015, p. 434-435.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  59. Published

    The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer. / Lin, Xue; Stenvang, Jan; Rasmussen, Mads Heilskov; Zhu, Shida; Jensen, Niels Frank; Tarpgaard, Line S.; Yang, Guangxia; Belling, Kirstine C.; Andersen, Claus Lindbjerg; Li, Jian; Bolund, Lars; Brunner, Nils.

    In: B M C Genomics, Vol. 16, No. 404, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  60. Published

    Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants. / J. Carmona, Santiago; Nielsen, Morten; Schafer-Nielsen, Claus; Mucci, Juan; Altcheh, Jaime; Balouz, Virginia; Tekiel, Valeria; C. Frasch, Alberto; Campetella, Oscar; A. Buscaglia, Carlos; Agüero, Fernán.

    In: Molecular & Cellular Proteomics, Vol. 14, No. 7, 2015, p. 1871-1884.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  61. Published

    Traces of ATCV-1 associated with laboratory component contamination. / Kjartansdóttir, Kristín Rós ; Friis-Nielsen, Jens; Asplund, Maria ; Mollerup, Sarah ; Mourier, Tobias ; Holm Jensen, Randi ; Arn Hansen, Thomas; Rey-Iglesia, Alba ; Raith Richter, Stine ; Alquezar-Planas, David E. ; Olsen, Pernille V. S. ; Vinner, Lasse ; Fridholm, Helena ; Sicheritz-Pontén, Thomas; Nielsen, Lars Peter; Brunak, Søren; Willerslev, Eske; Gonzalez-Izarzugaza, Jose Maria; Hansen, Anders Johannes .

    In: National Academy of Sciences. Proceedings, Vol. 112, No. 9, 2015, p. E925–E926.

    Publication: Research - peer-reviewLetter – Annual report year: 2015

  62. Published

    Transcriptome and genome size analysis of the venus flytrap. / Jensen, Michael Krogh; Vogt, Josef Korbinian; Bressendorff, Simon; Seguin-Orlando, Andaine; Petersen, Morten; Sicheritz-Pontén, Thomas; Mundy, John.

    In: P L o S One, Vol. 10, No. 4, e0123887, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  63. Published

    Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism. / Hao, Qin; Yadav, Rachita; Basse, Astrid L.; Petersen, Sidsel ; Sonne, Si B.; Rasmussen, Simon; Zhu, Qianhua; Lu, Zhike; Wang, Jun; Audouze, Karine Marie Laure; Gupta, Ramneek; Madsen, Lise; Kristiansen, Karsten; Hansen, Jacob B.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 308, No. 5, 2015, p. E380-E392.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  64. Published

    Two Lactococcus lactis thioredoxin paralogues play different roles in responses to arsenate and oxidative stress. / Efler, Petr; Kilstrup, Mogens; Johnsen, Stig; Svensson, Birte; Hägglund, Per.

    In: Microbiology, Vol. 161, No. Pt 3, 2015, p. 528-538.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  65. Published

    Whey-reduced weight gain is associated with a temporary growth reduction in young mice fed a high-fat diet. / Tranberg, Britt; Madsen, Andreas N.; Hansen, Axel K.; Hellgren, Lars.

    In: Journal of Nutritional Biochemistry, Vol. 26, No. 1, 2015, p. 9–15.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  66. 2014
  67. Published
  68. Published

    Acute and perinatal-programming effects of a fat-rich diet on rat muscle mitochondrial function and hepatic lipid accumulation.. / Hellgren, Lars; Jensen, Runa I.; Waterstradt, Michelle S. G. ; Quistorff, Bjørn; Lauritzen, Lotte.

    In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 93, 2014, p. 1170-1180.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  69. Published

    Adipose tissue trans fatty acids and changes in body weight and waist circumference. / Hansen, Camilla P.; Berentzen, Tina L.; Østergaard, Jane N.; Dahm, Christina C.; Hellgren, Lars; Schmidt, Erik B.; Tjønneland, Anne; Sørensen, Thorkild I. A.; Overvad, Kim; Jakobsen, Marianne U.

    In: The British Journal of Nutrition, Vol. 111, No. 7, 2014, p. 1283-1291.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  70. Published

    A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.. / Lindemose, Søren; Jensen, Michael Krogh; de Velde, Jan Van; O'Shea, Charlotte; Heyndrickx, Ken S.; Workman, Christopher; Vandepoele, Klaas; Skriver, Karen; De Masi, Federico.

    In: Nucleic Acids Research, Vol. 42, No. 12, 2014, p. 7681-7693.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  71. Published

    Ageing of atrazine in manure amended soils assessed by bioavailability to Pseudomonas sp. strain ADP. / Glæsner, Nadia; Bælum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    In: Biodegradation, Vol. 25, No. 2, 2014, p. 217-225.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  72. Published

    A Generally Applicable Translational Strategy Identifies S100A4 as a Candidate Gene in Allergy. / Bruhn, Sören; Fang, Yu; Barrenäs, Fredrik; Gustafsson, Mika; Zhang, Huan; Konstantinell, Aelita; Krönke, Andrea; Sönnichsen, Birte; Bresnick, Anne; Dulyaninova, Natalya; Wang, Hui; Zhao, Yelin; Klingelhöfer, Jörg; Ambartsumian, Noona; Beck, Mette Kristina; Nestor, Colm; Bona, Elsa; Xiang, Zou; Benson, Mikael.

    In: Science Translational Medicine, Vol. 6, No. 218, 2014, p. 20218ra4-218ra4.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  73. Published

    A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.. / Bønnelykke, Klaus; Sleiman, Patrick; Nielsen, Kasper; Kreiner-Møller, Eskil; Mercader, Josep M; Belgrave, Danielle; den Dekker, Herman T; Husby, Anders; Sevelsted, Astrid; Faura-Tellez, Grissel; Mortensen, Li Juel; Paternoster, Lavinia; Flaaten, Richard; Mølgaard, Anne; Smart, David E; Thomsen, Philip Francis; Rasmussen, Morten; Bonàs-Guarch, Silvia; Holst, Claus; Nohr, Ellen A; Yadav, Rachita; March, Michael E; Blicher, Thomas Holberg; Lackie, Peter M; Jaddoe, Vincent W V; Simpson, Angela; Holloway, John W; Duijts, Liesbeth; Custovic, Adnan; Davies, Donna E; Torrents, David; Gupta, Ramneek; Hollegaard, Mads Vilhelm; Hougaard, David M; Hakonarson, Hakon; Bisgaard, Hans Flinker.

    In: Nature Genetics, Vol. 46, 2014, p. 51-55.

    Publication: Research - peer-reviewLetter – Annual report year: 2013

  74. Published
  75. Published

    An elevated pro-inflammatory cytokine profile in multiple chemical sensitivity. / Dantoft, Thomas Meinertz; Elberling, J.; Pedersen, Susanne Brix; Szecsi, P.B.; Vesterhauge, S.; Skovbjerg, S.

    In: Psychoneuroendocrinology, Vol. 40, 2014, p. 140-150.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  76. Published

    An integrated catalog of reference genes in the human gut microbiome. / Li, Junhua; Jia, Huijue; Cai, Xianghang; Zhong, Huanzi; Feng, Qiang; Sunagawa, Shinichi; Arumugam, Manimozhiyan; Kultima, Jens Roat; Prifti, Edi; Nielsen, Trine; Juncker, Agnieszka; Nielsen, Henrik Bjørn; Brunak, Søren.

    In: Nature Biotechnology, Vol. 32, No. 8, 2014, p. 834-841.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  77. Published

    An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. / Brownstein, Catherine A ; Beggs, Alan H ; Homer, Nils ; Merriman, Barry ; Yu, Timothy W; Flannery, Katherine C ; DeChene, Elizabeth T ; Towne, Meghan C ; Savage, Sarah K ; Price, Emily N ; Dworzynski, Piotr.

    In: Genome Biology (Online Edition), Vol. 15, R53, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  78. Published

    Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. / Lundby, Alicia; Rossin, Elizabeth J.; Steffensen, Annette B.; Acha, Moshe Ray; Newton-Cheh, Christopher; Pfeufer, Arne; Lyneh, Stacey N.; Olesen, Søren-Peter; Brunak, Søren; Ellinor, Patrick T.; Jukema, J. Wouter; Trompet, Stella; Ford, Ian; Macfarlane, Peter W.; Krijthe, Bouwe P.; Hofman, Albert; Uitterlinden, Andre G.; Stricker, Bruno H.; Nathoe, Hendrik M.; Spiering, Wilko; Daly, Mark J.; Asselbergs, Folkert W.; van der Harst, Pim; Milan, David J.; de Bakker, Paul I. W.; Lage, Kasper; Olsen, Jesper V.

    In: Nature Methods, Vol. 11, No. 8, 2014, p. 868-874.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  79. Published
  80. Published

    Antibody informatics for drug discovery. / Shirai, Hiroki; Prades, Catherine; Vita, Randi; Marcatili, Paolo; Popovic, Bojana; Xu, Jianqing; Overington, John P.; Hirayama, Kazunori; Soga, Shinji; Tsunoyama, Kazuhisa; Clark, Dominic; Lefranc, Marie-Paule; Ikeda, Kazuyoshi.

    In: B B A - Proteins and Proteomics, Vol. 1844, No. 11, 2014, p. 2002-2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  81. Published

    Antibody structural modeling with prediction of immunoglobulin structure (PIGS).. / Marcatili, Paolo; Olimpieri, Pier Paolo; Chailyan, Anna; Tramontano, Anna.

    In: Nature Protocols, Vol. 9, No. 12, 2014, p. 2771-2783.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  82. Published

    A pan-cancer analysis of inferred homologous recombination deficiency identifies potential platinum benefit in novel subtypes. / Marquard, Andrea Marion; Eklund, Aron Charles; Wang, Zhigang C.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Birkbak, Nicolai Juul.

    In: Cancer Research, Vol. 74, No. 19 - Supplement, 2822, 2014.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2015

  83. Published
  84. Published
  85. Published

    A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records.. / Jiang, Li; Edwards, Stefan M.; Thomsen, Bo; Workman, Christopher; Guldbrandtsen, Bernt; Sørensen, Peter.

    In: BMC Bioinformatics, Vol. 15, No. 315, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  86. Published

    A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations. / Clemente, Florian J. ; Cardona, Alexia; Inchley, Charlotte E. ; Peter, Benjamin M. ; Jacobs, Guy; Pagani, Luca ; Lawson, Daniel J. ; Antão, Tiago ; Vicente, Mário ; Mitt, Mario ; Rasmussen, Simon.

    In: American Journal of Human Genetics, Vol. 95, No. 5, 2014, p. 584–589.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  87. Published
  88. Published

    Bacterial diversity in snow on North Pole ice floes. / Hauptmann, Aviaja Zenia Edna Lyberth; Stibal, Marek ; Bælum, Jacob; Sicheritz-Pontén, Thomas; Brunak, Søren; Bowman, Jeff S.; Hansen, Lars H. ; Jacobsen, Carsten S.; Blom, Nikolaj.

    In: Extremophiles, Vol. 18, 2014, p. 945-951.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  89. Published
  90. Published

    Biological insights from 108 schizophrenia-associated genetic loci. / Ripke, Stephan; Neale, Benjamin M.; Corvin, Aiden ; Walters, James T. R. ; Farh, Kai-How ; Holmans, Peter A. ; Lee, Phil ; Bulik-Sullivan, Brendan ; Collier, David A. ; Huang, Hailiang ; Pers, Tune Hannes; Agerbo, Esben ; Demontis, Ditte ; Hansen, Thomas; Hollegaard, Mads Vilhelm; Hougaard, David M.; Mors, Ole; Werge, Thomas.

    In: Nature, Vol. 511, 2014, p. 421-427.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  91. Published

    Cesarean section imprints cord blood immune cell distributions. / Thysen, Anna Hammerich; Larsen, Jeppe Madura; Rasmussen, Mette Annelie; Stokholm, J.; Bønnelykke, K.; Pedersen, Susanne Brix; Bisgaard, Hans Flinker.

    In: ALLERGY, Vol. 69, No. Supplement s99, 438, 2014, p. 192-192.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  92. Published

    Characterisation of the Ara h 1-specific IgE repertoire in peanut allergic patients using phage display technology and next generation sequencing. / Christiansen, Anders; Bøgh, Katrine Lindholm; Kringelum, Jens Vindahl; Hansen, Christian Skjødt; Rigby, N. M.; Eiwegger, T.; Szepfalusi, Z.; Lund, Ole; Dufva, Martin.

    In: ALLERGY, Vol. 69, No. Supplement, 297, 2014, p. 140-140.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  93. Published

    Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery.. / Hansen, Andreas M.; Rasmussen, Michael; Svitek, Nicholas; Harndahl, Mikkel; Golde, William T.; Barlow, John; Nene, Vishvanath; Buus, Søren; Nielsen, Morten.

    In: Immunogenetics, Vol. 66, No. 12, 2014, p. 705-718.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  94. Published

    Children developing asthma by school-age display aberrant immune responses to pathogenic airway bacteria as infants. / Larsen, Jeppe Madura; Pedersen, Susanne Brix; Thysen, Anna Hammerich; Birch, S.; Rasmussen, M.A.; Bisgaard, H.

    In: ALLERGY, Vol. 69, No. s99, 404, 2014, p. 179-179.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2014

  95. Published

    Children with asthma by school age display aberrant immune responses to pathogenic airway bacteria as infants. / Larsen, Jeppe Madura; Pedersen, Susanne Brix; Thysen, Anna Hammerich; Birch, Sune; Rasmussen, Morten Arendt; Bisgaard, Hans Flinker.

    In: Journal of Allergy and Clinical Immunology, Vol. 133, No. 4, 2014, p. 1008-1013.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  96. Published
  97. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds. / Geertz-Hansen, Henrik Marcus; Blom, Nikolaj; Feist, Adam; Brunak, Søren; Petersen, Thomas Nordahl.

    In: Proteins, Vol. 82, No. 9, 2014, p. 1819-1828.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  98. Published
  99. Published

    Combining Experiments and Simulations Using the Maximum Entropy Principle. / Boomsma, Wouter; Ferkinghoff-Borg, Jesper; Lindorff-Larsen, Kresten.

    In: P L o S Computational Biology (Online), Vol. 10, No. 2, e1003406, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  100. Published

    Comparison of the Web Tools ARG-ANNOT and ResFinder for Detection of Resistance Genes in Bacteria. / Zankari, Ea.

    In: Antimicrobial Agents and Chemotherapy, Vol. 58, No. 8, 2014, p. 4986-4986.

    Publication: Research - peer-reviewLetter – Annual report year: 2014

  101. Published

    Compass: A hybrid method for clinical and biobank data mining. / Krysiak-Baltyn, Konrad; Petersen, Thomas Nordahl; Audouze, Karine Marie Laure; Jørgensen, Niels; Ängquist, L.; Brunak, Søren.

    In: Journal of Biomedical Informatics, Vol. 47, 2014, p. 160-170.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  102. Published

    Complete Genome Sequence of Border Disease Virus Genotype 3 Strain Gifhorn. / Fahnøe, Ulrik; Höper, Dirk ; Beer, Martin; Rasmussen, Thomas Bruun.

    In: Genome Announcements, Vol. 2, No. 1, e01142-13, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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